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Study · Non-randomized trial · 1987

2 results

[Nonspecific and antigen-specific adhesiveness of circulating lymphocytes in dysentery patients undergoing combined therapy using thymalin and indomethacin].

Mats AN, Cheprasova EV, Elkina SI, Koriakin EV

Zhurnal mikrobiologii, epidemiologii i immunobiologii1 May 1987

PMID2441548 (opens in a new tab)PepBankPUB-02441548
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. 2 results from people.

  1. 01HumanNon-randomized trialEfficacy outcome

    In dysentery patients, thymalin did not accelerate normalization of nonspecific lymphocyte adhesiveness during disease regression.

    In plain wordsIn dysentery patients, thymalin did not accelerate the return of nonspecific lymphocyte adhesiveness to normal.

    Peptide
    Thymalin
    Outcome
    No significant changeNormalization of nonspecific lymphocyte adhesiveness
    Study

    n: not reported in source

    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Short courses of treatment with indomethacin, but not with thymalin (the preparation of thymic hormones), used for immunomodulation, have accelerated the normalization of nonspecific lymphocyte adhesiveness during regression of the disease
    1 context sentence
    Summary · context
    Nonspecific adhesiveness of lymphocytes to polyacrylonitrile fiber and the antigen-specific adhesiveness of T-lymphocytes to Shigella flexneri pellicular immunosorbent have been studied in dysentery patients.
  2. 02HumanNon-randomized trialMechanism

    In dysentery patients, thymalin did not inhibit antigen-specific T-lymphocyte adhesiveness, unlike indomethacin.

    In plain wordsIn dysentery patients, thymalin did not inhibit antigen-specific T-lymphocyte adhesiveness, unlike indomethacin.

    Peptide
    Thymalin
    Outcome
    No significant changeAntigen-specific T-lymphocyte adhesiveness
    Study

    n: not reported in source

    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    Dose not stated

    Source sentences

    Summary
    while indomethacin, in contrast to thymalin, inhibits antigen-specific T-lymphocyte adhesiveness which increases with the development of immune response.
    1 context sentence
    Summary · context
    Nonspecific adhesiveness of lymphocytes to polyacrylonitrile fiber and the antigen-specific adhesiveness of T-lymphocytes to Shigella flexneri pellicular immunosorbent have been studied in dysentery patients.

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Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    14 Oct 2026, 05:02 UTC

    Study results updated

  2. Version 1

    14 Oct 2026, 01:46 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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