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Study · In vitro (cells) · 1990

4 results

Structure and immunological properties of thymosin beta 9 Met, a new analog of thymosin beta 4 isolated from porcine thymus.

Low TL, Lin CY, Pan TL, Chiou AJ, Tsugita A

International journal of peptide and protein research1 Dec 1990Cited by 7 (Europe PMC)

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

3 results from studies that gave the peptide. No result from this study comes from people.

  1. 01LabIn vitro (cells)Activity measurement

    In cord blood lymphocytes, thymosin beta‑4 enhanced gamma-interferon production less than thymosin beta 9 Met did.

    In plain wordsIn lab tests on cord blood cells, thymosin beta‑4 raised gamma-interferon less than thymosin beta 9 Met.

    Outcome
    DecreaseGamma-interferon production
    Study

    n: not reported in source

    cord blood lymphocytes
    Comparator
    Thymosin beta 9 Met
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Biologically, thymosin beta 9 Met was found to be more active than beta 4 in enhancing gamma-interferon production in cord blood lymphocytes.
  2. 02LabIn vitro (cells)Activity measurement

    In cord blood lymphocytes, thymosin beta‑4 stimulated higher amounts of interleukin 2 than thymosin beta 9 Met did.

    In plain wordsIn lab tests on cord blood cells, thymosin beta‑4 raised interleukin 2 more than thymosin beta 9 Met.

    Outcome
    IncreaseInterleukin 2 production
    Study

    n: not reported in source

    cord blood lymphocytes
    Comparator
    Thymosin beta 9 Met
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    Dose not stated

    Source sentences

    Summary
    However, beta 4 appeared to stimulate higher amounts of interleukin 2 and tumor necrotic factor.
  3. 03LabIn vitro (cells)Activity measurement

    In cord blood lymphocytes, thymosin beta‑4 stimulated higher amounts of tumor necrotic factor than thymosin beta 9 Met did.

    In plain wordsIn lab tests on cord blood cells, thymosin beta‑4 raised tumor necrotic factor more than thymosin beta 9 Met.

    Outcome
    IncreaseTumor necrotic factor production
    Study

    n: not reported in source

    cord blood lymphocytes
    Comparator
    Thymosin beta 9 Met
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    Dose not stated

    Source sentences

    Summary
    However, beta 4 appeared to stimulate higher amounts of interleukin 2 and tumor necrotic factor.

Natural levels measured1

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 04AnimalEndogenous levelAnimal study (in vivo)Other

    In porcine tissues, thymosin beta‑4 was recovered at the highest level in spleen (203 micrograms/g tissue) and at lower levels in thymus, kidney, liver, brain and heart.

    In plain wordsIn pigs, the body's own thymosin beta‑4 was found in many organs, with the most in the spleen.

    Outcome
    Not applicableThymosin beta 4 recovery in porcine tissues
    Study

    pign: not reported in source

    Outcome group
    Endogenous peptide levels · Whole body

    Measurements

    Thymosin beta 4 recovery
    85 micrograms/g tissue
    thymus
    Thymosin beta 4 recovery
    203 micrograms/g tissue
    spleen
    Thymosin beta 4 recovery
    31 micrograms/g tissue
    liver
    Thymosin beta 4 recovery
    10 micrograms/g tissue
    heart
    Thymosin beta 4 recovery
    51 micrograms/g tissue
    kidney
    Thymosin beta 4 recovery
    31 micrograms/g tissue
    brain

    Source sentences

    Summary
    The recoveries of beta 9 Met, beta 4, and prothymosin alpha in porcine tissues have been determined (in micrograms/g tissue) as follows: thymus (43, 85, 133); spleen (68, 203, 37); liver (10, 31, 27); heart (1.5, 10, 0); kidney (5, 51, 37); brain (0.8, 31, 5).

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 01:52 UTC

    Study results updated

  2. Version 1

    12 Oct 2026, 18:17 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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