In human tissues, thymosin beta‑4 mRNA was more abundant in malignant renal tumors than in normal tissues.
In plain wordsHuman kidney tumors had more of the body's own thymosin beta‑4 messenger RNA than normal tissues.
- Peptide
- Thymosin beta-4 (human)
- Outcome
- IncreaseThymosin beta 4 mRNA in malignant renal tumors
- Study
n: not reported in source
- Comparator
- Normal tissues
- Outcome group
- Gene expression · Cancer
Source sentences
Low levels of beta 4 and beta 10 mRNA species prevailed in normal tissues; in contrast, these gene transcripts were notably more abundant in malignant renal tumors and in the normal human embryonic kidney.
1 context sentence(design, population, supporting numbers)
These observations prompted the present study which has used cDNA and synthetic oligonucleotide probes in combination with high-performance liquid chromatography (HPLC) to examine the differential expression of these 2 genes in normal and neoplastic human tissues and in the developing human kidney.
This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.