Stability and purity profile of gonadorelin acetate: a high-purity gonadotropin-releasing hormone.

Wong W, Mercorelli M, DeLuccia F, Young R, Lane PA, Hoerig J, Turan A

International journal of fertility1 Sept 1990Cited by 1 (Europe PMC)

PMID1980667PepBankPUB-01980667

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone3

In this study, Gonadorelin (GnRH, LHRH) was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Gonadorelin (GnRH, LHRH).

01LabNot a test of Gonadorelin (GnRH, LHRH) aloneIn vitro (cell-free)Other
In stability testing, gonadorelin acetate drug substance was stable for at least 12 months at 24 degrees C and 50% relative humidity, with no degradation under accelerated storage.
In plain wordsIn lab tests, gonadorelin acetate powder stayed stable for at least 12 months at 24 degrees C and showed no breakdown under harsh storage.
Peptide
Gonadorelin (GnRH, LHRH)
Outcome
Not applicableDrug substance stability
Study
n: not reported in source
HPLC stability testing
Outcome group
Formulation, delivery and stability · Pharmacology
Measurements
stability duration
≥ 12 months
24 degrees C, 50% relative humidity
Source sentences
Summary
The gonadorelin acetate drug substance was found to be stable for at least 12 months when stored at 24 degrees C in 50% relative humidity, and showed no degradation even under accelerated storage conditions.
1 context sentence(design, population, supporting numbers)
Summary · context
Both the purity and potency of the drug substance, the lyophilized product for injection, and the reconstituted material that would be transferred to the infusion pump system were monitored using high-performance liquid chromatography.
In this study, Gonadorelin (GnRH, LHRH) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Gonadorelin (GnRH, LHRH).
Report a problemFND-0198066701
02LabNot a test of Gonadorelin (GnRH, LHRH) aloneIn vitro (cell-free)Other
In stability testing, the lyophilized gonadorelin acetate product was stable for at least 18 months at 24 degrees C and 50% relative humidity.
In plain wordsIn lab tests, the freeze-dried gonadorelin acetate product stayed stable for at least 18 months at 24 degrees C.
Peptide
Gonadorelin (GnRH, LHRH)
Outcome
Not applicableLyophilized product stability
Study
n: not reported in source
HPLC stability testing
Outcome group
Formulation, delivery and stability · Pharmacology
Measurements
stability duration
≥ 18 months
24 degrees C, 50% relative humidity
Source sentences
Summary
Similarly, the lyophilized product also showed excellent stability for at least 18 months when stored at 24 degrees C in 50% relative humidity.
1 context sentence(design, population, supporting numbers)
Summary · context
Both the purity and potency of the drug substance, the lyophilized product for injection, and the reconstituted material that would be transferred to the infusion pump system were monitored using high-performance liquid chromatography.
In this study, Gonadorelin (GnRH, LHRH) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Gonadorelin (GnRH, LHRH).
Report a problemFND-0198066702
03LabNot a test of Gonadorelin (GnRH, LHRH) aloneIn vitro (cell-free)Other
In stability testing, reconstituted gonadorelin acetate was stable for at least 45 days at 24 degrees C or 37 degrees C.
In plain wordsIn lab tests, gonadorelin acetate mixed into solution stayed stable for at least 45 days at 24 or 37 degrees C.
Peptide
Gonadorelin (GnRH, LHRH)
Outcome
Not applicableReconstituted solution stability
Study
n: not reported in source
HPLC stability testing
Outcome group
Formulation, delivery and stability · Pharmacology
Measurements
stability duration
≥ 45 days
24 or 37 degrees C
Source sentences
Summary
Upon reconstitution, gonadorelin acetate was found to be stable for at least 45 days when stored at 24 degrees C or 37 degrees C.
1 context sentence(design, population, supporting numbers)
Summary · context
Both the purity and potency of the drug substance, the lyophilized product for injection, and the reconstituted material that would be transferred to the infusion pump system were monitored using high-performance liquid chromatography.
In this study, Gonadorelin (GnRH, LHRH) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Gonadorelin (GnRH, LHRH).
Report a problemFND-0198066703

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

Version 2Current
13 Oct 2026, 21:44 UTC
Study results updated
Version 1
13 Oct 2026, 16:31 UTC
First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

Journal Article

MeSH terms

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