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Study · Measured the body's own peptide · 1990

4 results

Developmental expression of mRNAs encoding thymosins beta 4 and beta 10 in rat brain and other tissues.

Lin SC, Morrison-Bogorad M

Journal of molecular neuroscience : MN1 Jan 1990Cited by 64 (Europe PMC)

PMID1979498 (opens in a new tab)DOI10.1007/bf02896924 (opens in a new tab)PepBankPUB-01979498
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

No result from this study comes from a test of the peptide.

Natural levels measured4

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01AnimalEndogenous levelAnimal study (in vivo)Other

    In fetal rats, thymosin beta‑4 mRNA was present at highest levels in cortex and cerebellum and at varying levels in other fetal tissues.

    In plain wordsIn rat fetuses, the body's own thymosin beta‑4 messenger RNA was highest in the cortex and cerebellum.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    Not applicableThymosin beta 4 mRNA in fetal tissues
    Study

    ratn: not reported in source

    Outcome group
    Gene expression · Nervous system and cognition

    Source sentences

    Summary
    we showed that both thymosin mRNAs were present at highest levels in fetal cortex and cerebellum but also were present at varying levels in all other fetal tissues examined (thymus, spleen, lung, kidney, adrenal, heart, and liver).

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

  2. 02AnimalEndogenous levelAnimal study (in vivo)Other

    In developing rat brain, thymosin beta‑4 mRNA levels dropped much less sharply than thymosin beta 10 mRNA levels.

    In plain wordsIn rats, the body's own thymosin beta‑4 messenger RNA fell during brain development, but less sharply than thymosin beta 10.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    DecreaseThymosin beta 4 mRNA during brain development
    Study

    ratn: not reported in source

    Comparator
    Thymosin beta 10 mRNA
    Outcome group
    Gene expression · Nervous system and cognition

    Source sentences

    Summary
    Thymosin beta 4 mRNA levels dropped much less sharply during brain development than did levels of the beta 10 mRNA.

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

  3. 03AnimalEndogenous levelAnimal study (in vivo)Other

    In rats, thymosin beta‑4 mRNA levels remained relatively constant during development of thymus, spleen and lung.

    In plain wordsIn rats, the body's own thymosin beta‑4 messenger RNA stayed fairly constant as the thymus, spleen and lung developed.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    No significant changeThymosin beta 4 mRNA during thymus, spleen and lung development
    Study

    ratn: not reported in source

    Outcome group
    Gene expression · Immune and inflammation

    Source sentences

    Summary
    Levels of both thymosin beta 10 and beta 4 mRNAs remained relatively constant during development of thymus, spleen, and lung.

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

  4. 04AnimalEndogenous levelAnimal study (in vivo)Other

    In adult rats, testis and ovary contained little thymosin beta‑4 mRNA.

    In plain wordsIn adult rats, testis and ovary had little of the body's own thymosin beta‑4 messenger RNA.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    Not applicableThymosin beta 4 mRNA in adult testis and ovary
    Study

    ratn: not reported in source

    Outcome group
    Gene expression · Reproductive and sexual health

    Source sentences

    Summary
    Testis and ovary contained the highest relative levels of thymosin beta 10 mRNA among adult tissues, but little thymosin beta 4 mRNA.

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 01:52 UTC

    Study results updated

  2. Version 1

    12 Oct 2026, 18:17 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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