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Study · Measured the body's own peptide · 1991

2 results

Differential modulation of thymosin genes in the immature rat ovary by gonadotropins.

Hall AK, Aten R, Behrman HR

Molecular and cellular endocrinology1 Aug 1991Cited by 7 (Europe PMC)

PMID1936544 (opens in a new tab)DOI10.1016/0303-7207(91)90093-8 (opens in a new tab)PepBankPUB-01936544
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Natural levels measured2

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01AnimalEndogenous levelAnimal study (in vivo)Mechanism

    In immature rats, ovarian thymosin beta‑4 gene transcription varied little after pregnant mare's serum gonadotropin.

    In plain wordsIn immature rats, the ovary's own thymosin beta‑4 gene activity changed little after a gonadotropin hormone.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    No significant changeOvarian thymosin beta-4 gene expression after PMSG
    Study

    ratn: not reported in source

    Immature rat ovary
    Outcome group
    Endogenous peptide levels · Reproductive and sexual health

    Source sentences

    Summary
    In contrast, the transcriptional status of the thymosin beta-4 gene varied little in response to the PMSG.
    1 context sentence
    Summary · context
    A cloned thymosin beta-10 cDNA and a synthetic oligonucleotide specific for the thymosin beta-4 gene were used to study the in vivo expression of these two genes in the immature rat ovary in response to exogenously administered gonadotropins.

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

  2. 02AnimalEndogenous levelAnimal study (in vivo)Mechanism

    In PMSG-primed immature rats, human chorionic gonadotropin stimulated ovarian thymosin beta‑4 gene expression.

    In plain wordsIn immature rats, a second hormone treatment raised the ovary's own thymosin beta‑4 gene activity.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    IncreaseOvarian thymosin beta-4 gene expression after hCG in PMSG-primed rats
    Study

    ratn: not reported in source

    Immature rat ovary
    Outcome group
    Endogenous peptide levels · Reproductive and sexual health

    Source sentences

    Summary
    Administration of human chorionic gonadotropin (hCG) to PMSG-primed rats inhibited ovarian thymosin beta-10 but stimulated thymosin beta-4 gene expression.
    1 context sentence
    Summary · context
    A cloned thymosin beta-10 cDNA and a synthetic oligonucleotide specific for the thymosin beta-4 gene were used to study the in vivo expression of these two genes in the immature rat ovary in response to exogenously administered gonadotropins.

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 01:52 UTC

    Study results updated

  2. Version 1

    12 Oct 2026, 18:17 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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