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Study · Measured the body's own peptide · 1991

2 results

Retinoic acid regulates thymosin beta 10 levels in rat neuroblastoma cells.

Hall AK, Chen SC, Hempstead JL, Morgan JI

Journal of neurochemistry1 Feb 1991Cited by 22 (Europe PMC)

PMID1846397 (opens in a new tab)DOI10.1111/j.1471-4159.1991.tb08173.x (opens in a new tab)PepBankPUB-01846397
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Natural levels measured2

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01LabEndogenous levelIn vitro (cells)Mechanism

    In rat neuroblastoma cell lines, retinoic acid increased thymosin beta 10 content but did not change thymosin beta‑4 content.

    In plain wordsIn rat nerve tumour cells, retinoic acid did not change the cells' own thymosin beta‑4 level.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    No significant changeThymosin beta 4 content after retinoic acid
    Study

    ratn: not reported in source

    Rat neuroblastoma cell lines (B103, B104)
    Outcome group
    Endogenous peptide levels · Nervous system and cognition

    Source sentences

    Summary
    In several neuroblastomas, including the B103 and B104 lines, retinoic acid elicits a time- and dose-dependent increase in the content of thymosin beta 10, but not that of thymosin beta 4.
    1 context sentence
    Summary · context
    Because some of these cell lines respond to exogenously applied agents by increasing their apparent state of differentiation, we have determined whether thymosin beta 10 levels are coordinately modulated.

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

  2. 02LabEndogenous levelIn vitro (cells)Mechanism

    In rat neuroblastoma cells, the mRNA for thymosin beta‑4 was unaffected by retinoic acid.

    In plain wordsIn rat nerve tumour cells, retinoic acid did not change the mRNA for the body's own thymosin beta‑4 levels.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    No significant changeThymosin beta 4 mRNA after retinoic acid
    Study

    ratn: not reported in source

    Rat neuroblastoma cell lines (B103, B104)
    Outcome group
    Endogenous peptide levels · Nervous system and cognition

    Source sentences

    Summary
    The mRNA for thymosin beta 4 is unaffected by retinoic acid.
    1 context sentence
    Summary · context
    Because some of these cell lines respond to exogenously applied agents by increasing their apparent state of differentiation, we have determined whether thymosin beta 10 levels are coordinately modulated.

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 01:52 UTC

    Study results updated

  2. Version 1

    12 Oct 2026, 18:17 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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