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Study · Not a test of the peptide alone · 1991

10 results

[Effect of thymus preparations and anti-tuberculosis agents on immunologic reactivity and the course of the tuberculosis process in experimental animals].

Demidov SV, Miasnikov VG, Chernushenko EF, Osipova LS

Problemy tuberkuleza1 Jan 1991Cited by 3 (Europe PMC)

PMID1803376 (opens in a new tab)PepBankPUB-01803376
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study10

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone10

In this study, the peptide was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking the peptide.

  1. 01AnimalNot a test of Thymalin aloneAnimal study (in vivo)Efficacy outcome

    In mice with tuberculosis, pooled thymus preparations including thymalin increased lifespan versus antituberculous drugs alone.

    In plain wordsIn mice with tuberculosis, pooled thymus preparations including thymalin increased lifespan compared with antituberculous drugs alone.

    Peptide
    Thymalin
    Outcome
    IncreaseLifespan
    Study

    CBA micen: not reported in source

    Experimental tuberculosis
    Comparator
    Antituberculous drugs alone
    Outcome group
    Mortality · Whole body

    Source sentences

    Summary
    Thymus preparations supplemented to the complex treatment of experimental tuberculosis significantly increased their lifespan,
    2 context sentences
    Summary · context
    as compared to those on antituberculous drugs alone.
    Summary · context
    The effects of thymogen, thymalin and vilosen in combination with antituberculous drugs (isoniazid, streptomycin, rifampicin) were studied on 240 CBA mice with experimental tuberculosis.

    In this study, Thymalin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymalin.

  2. 02AnimalNot a test of Thymalin aloneAnimal study (in vivo)Efficacy outcome

    In mice with tuberculosis, pooled thymus preparations including thymalin decreased spleen weight index versus antituberculous drugs alone.

    In plain wordsIn mice with tuberculosis, pooled thymus preparations including thymalin reduced spleen weight index compared with antituberculous drugs alone.

    Peptide
    Thymalin
    Outcome
    DecreaseSpleen weight index
    Study

    CBA micen: not reported in source

    Experimental tuberculosis
    Comparator
    Antituberculous drugs alone
    Outcome group
    Immune response · Immune and inflammation

    Source sentences

    Summary
    contributed to a decrease in the index of spleen weight lung density
    2 context sentences
    Summary · context
    as compared to those on antituberculous drugs alone.
    Summary · context
    The effects of thymogen, thymalin and vilosen in combination with antituberculous drugs (isoniazid, streptomycin, rifampicin) were studied on 240 CBA mice with experimental tuberculosis.

    In this study, Thymalin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymalin.

  3. 03AnimalNot a test of Thymalin aloneAnimal study (in vivo)Efficacy outcome

    In mice with tuberculosis, pooled thymus preparations including thymalin decreased lung density versus antituberculous drugs alone.

    In plain wordsIn mice with tuberculosis, pooled thymus preparations including thymalin reduced lung density compared with antituberculous drugs alone.

    Peptide
    Thymalin
    Outcome
    DecreaseLung density
    Study

    CBA micen: not reported in source

    Experimental tuberculosis
    Comparator
    Antituberculous drugs alone
    Outcome group
    Lung injury and fibrosis · Respiratory

    Source sentences

    Summary
    contributed to a decrease in the index of spleen weight lung density
    2 context sentences
    Summary · context
    as compared to those on antituberculous drugs alone.
    Summary · context
    The effects of thymogen, thymalin and vilosen in combination with antituberculous drugs (isoniazid, streptomycin, rifampicin) were studied on 240 CBA mice with experimental tuberculosis.

    In this study, Thymalin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymalin.

  4. 04AnimalNot a test of Thymalin aloneAnimal study (in vivo)Efficacy outcome

    In mice with tuberculosis, pooled thymus preparations including thymalin increased T lymphocyte count versus antituberculous drugs alone.

    In plain wordsIn mice with tuberculosis, pooled thymus preparations including thymalin increased T lymphocyte counts compared with antituberculous drugs alone.

    Peptide
    Thymalin
    Outcome
    IncreaseT lymphocyte count
    Study

    CBA micen: not reported in source

    Experimental tuberculosis
    Comparator
    Antituberculous drugs alone
    Outcome group
    Immune response · Immune and inflammation

    Source sentences

    Summary
    and significantly increased the count of T lymphocytes and their proliferative activity as compared to those on antituberculous drugs alone.
    1 context sentence
    Summary · context
    The effects of thymogen, thymalin and vilosen in combination with antituberculous drugs (isoniazid, streptomycin, rifampicin) were studied on 240 CBA mice with experimental tuberculosis.

    In this study, Thymalin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymalin.

  5. 05AnimalNot a test of Thymalin aloneAnimal study (in vivo)Efficacy outcome

    In mice with tuberculosis, pooled thymus preparations including thymalin increased T lymphocyte proliferation versus antituberculous drugs alone.

    In plain wordsIn mice with tuberculosis, pooled thymus preparations including thymalin increased T lymphocyte proliferation compared with antituberculous drugs alone.

    Peptide
    Thymalin
    Outcome
    IncreaseT lymphocyte proliferative activity
    Study

    CBA micen: not reported in source

    Experimental tuberculosis
    Comparator
    Antituberculous drugs alone
    Outcome group
    Immune response · Immune and inflammation

    Source sentences

    Summary
    and significantly increased the count of T lymphocytes and their proliferative activity as compared to those on antituberculous drugs alone.
    1 context sentence
    Summary · context
    The effects of thymogen, thymalin and vilosen in combination with antituberculous drugs (isoniazid, streptomycin, rifampicin) were studied on 240 CBA mice with experimental tuberculosis.

    In this study, Thymalin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymalin.

  6. 06AnimalNot a test of Thymogen (oglufanide) aloneAnimal study (in vivo)Efficacy outcome

    In mice with tuberculosis, pooled thymus preparations including thymogen added to antituberculous drugs significantly increased lifespan versus antituberculous drugs alone.

    In plain wordsIn mice with tuberculosis, thymus preparations including thymogen added to tuberculosis drugs increased lifespan versus tuberculosis drugs alone.

    Peptide
    Thymogen (oglufanide)
    Outcome
    IncreaseLifespan
    Study

    mousen: not reported in source

    CBA mice with experimental tuberculosis
    Comparator
    Antituberculous drugs alone
    Outcome group
    Mortality · Infection

    Source sentences

    Summary
    Thymus preparations supplemented to the complex treatment of experimental tuberculosis significantly increased their lifespan, contributed to a decrease in the index of spleen weight lung density and significantly increased the count of T lymphocytes and their proliferative activity as compared to t…
    1 context sentence
    Summary · context
    The effects of thymogen, thymalin and vilosen in combination with antituberculous drugs (isoniazid, streptomycin, rifampicin) were studied on 240 CBA mice with experimental tuberculosis.

    In this study, Thymogen (oglufanide) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymogen (oglufanide).

  7. 07AnimalNot a test of Thymogen (oglufanide) aloneAnimal study (in vivo)Efficacy outcome

    In mice with tuberculosis, pooled thymus preparations including thymogen added to antituberculous drugs decreased spleen weight index versus antituberculous drugs alone.

    In plain wordsIn mice with tuberculosis, thymus preparations including thymogen added to tuberculosis drugs decreased spleen weight index versus tuberculosis drugs alone.

    Peptide
    Thymogen (oglufanide)
    Outcome
    DecreaseSpleen weight index
    Study

    mousen: not reported in source

    CBA mice with experimental tuberculosis
    Comparator
    Antituberculous drugs alone
    Outcome group
    Immune response · Infection

    Source sentences

    Summary
    Thymus preparations supplemented to the complex treatment of experimental tuberculosis significantly increased their lifespan, contributed to a decrease in the index of spleen weight lung density and significantly increased the count of T lymphocytes and their proliferative activity as compared to t…
    1 context sentence
    Summary · context
    The effects of thymogen, thymalin and vilosen in combination with antituberculous drugs (isoniazid, streptomycin, rifampicin) were studied on 240 CBA mice with experimental tuberculosis.

    In this study, Thymogen (oglufanide) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymogen (oglufanide).

  8. 08AnimalNot a test of Thymogen (oglufanide) aloneAnimal study (in vivo)Efficacy outcome

    In mice with tuberculosis, pooled thymus preparations including thymogen added to antituberculous drugs decreased lung density versus antituberculous drugs alone.

    In plain wordsIn mice with tuberculosis, thymus preparations including thymogen added to tuberculosis drugs decreased lung density versus tuberculosis drugs alone.

    Peptide
    Thymogen (oglufanide)
    Outcome
    DecreaseLung density
    Study

    mousen: not reported in source

    CBA mice with experimental tuberculosis
    Comparator
    Antituberculous drugs alone
    Outcome group
    Infection and antimicrobial activity · Infection

    Source sentences

    Summary
    Thymus preparations supplemented to the complex treatment of experimental tuberculosis significantly increased their lifespan, contributed to a decrease in the index of spleen weight lung density and significantly increased the count of T lymphocytes and their proliferative activity as compared to t…
    1 context sentence
    Summary · context
    The effects of thymogen, thymalin and vilosen in combination with antituberculous drugs (isoniazid, streptomycin, rifampicin) were studied on 240 CBA mice with experimental tuberculosis.

    In this study, Thymogen (oglufanide) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymogen (oglufanide).

  9. 09AnimalNot a test of Thymogen (oglufanide) aloneAnimal study (in vivo)Efficacy outcome

    In mice with tuberculosis, pooled thymus preparations including thymogen added to antituberculous drugs significantly increased T lymphocyte counts versus antituberculous drugs alone.

    In plain wordsIn mice with tuberculosis, thymus preparations including thymogen added to tuberculosis drugs increased T lymphocyte counts versus tuberculosis drugs alone.

    Peptide
    Thymogen (oglufanide)
    Outcome
    IncreaseT lymphocyte count
    Study

    mousen: not reported in source

    CBA mice with experimental tuberculosis
    Comparator
    Antituberculous drugs alone
    Outcome group
    Immune response · Infection

    Source sentences

    Summary
    Thymus preparations supplemented to the complex treatment of experimental tuberculosis significantly increased their lifespan, contributed to a decrease in the index of spleen weight lung density and significantly increased the count of T lymphocytes and their proliferative activity as compared to t…
    1 context sentence
    Summary · context
    The effects of thymogen, thymalin and vilosen in combination with antituberculous drugs (isoniazid, streptomycin, rifampicin) were studied on 240 CBA mice with experimental tuberculosis.

    In this study, Thymogen (oglufanide) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymogen (oglufanide).

  10. 10AnimalNot a test of Thymogen (oglufanide) aloneAnimal study (in vivo)Efficacy outcome

    In mice with tuberculosis, pooled thymus preparations including thymogen added to antituberculous drugs significantly increased T lymphocyte proliferation versus antituberculous drugs alone.

    In plain wordsIn mice with tuberculosis, thymus preparations including thymogen added to tuberculosis drugs increased T lymphocyte proliferation versus tuberculosis drugs alone.

    Peptide
    Thymogen (oglufanide)
    Outcome
    IncreaseT lymphocyte proliferative activity
    Study

    mousen: not reported in source

    CBA mice with experimental tuberculosis
    Comparator
    Antituberculous drugs alone
    Outcome group
    Immune response · Infection

    Source sentences

    Summary
    Thymus preparations supplemented to the complex treatment of experimental tuberculosis significantly increased their lifespan, contributed to a decrease in the index of spleen weight lung density and significantly increased the count of T lymphocytes and their proliferative activity as compared to t…
    1 context sentence
    Summary · context
    The effects of thymogen, thymalin and vilosen in combination with antituberculous drugs (isoniazid, streptomycin, rifampicin) were studied on 240 CBA mice with experimental tuberculosis.

    In this study, Thymogen (oglufanide) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymogen (oglufanide).

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    21 Oct 2026, 12:50 UTC

    Study data updated · source update from Europe PMC

  2. Version 2

    14 Oct 2026, 05:02 UTC

    Study results updated

  3. Version 1

    14 Oct 2026, 01:46 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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