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Study · Measured the body's own peptide · 1992

3 results

Evidence for the extranuclear localization of thymosins in thymus.

Tsitsiloni OE, Yialouris PP, Echner H, Voelter W, Haritos AA

Experientia1 Apr 1992Cited by 10 (Europe PMC)

PMID1582498 (opens in a new tab)DOI10.1007/bf01923441 (opens in a new tab)PepBankPUB-01582498
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

No result from this study comes from a test of the peptide.

Natural levels measured1

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01AnimalEndogenous levelAnimal study (in vivo)Other

    In calf thymus, the bulk of thymosin beta‑4 was found in the extranuclear material and only traces in the nuclear environment.

    In plain wordsIn calf thymus, the body's own thymosin beta‑4 was mostly outside the cell nucleus and only traces were inside it.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    Not applicableSubcellular localization of thymosin beta 4 in calf thymus
    Study

    calfn: not reported in source

    Nuclear and extranuclear extracts of calf thymus
    Outcome group
    Endogenous peptide levels · Immune and inflammation

    Source sentences

    Summary
    The bulk of these polypeptides was found in the extranuclear material whereas only traces were observed in the nuclear environment, which indicates the extranuclear localisation of alpha- and beta-thymosins.
    1 context sentence
    Summary · context
    This radioimmunoassay, together with an improved radioimmunoassay for the N-terminus of parathymosin alpha, was employed for the measurement of the levels of thymosin beta 4 and parathymosin alpha in nuclear and extranuclear extracts of calf thymus.

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

Studies that did not test the peptide alone2

In this study, Thymosin beta-4 (human) was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Thymosin beta-4 (human).

  1. 02LabNot a test of Thymosin beta-4 (human) aloneIn vitro (cell-free)Other

    The new thymosin beta‑4 radioimmunoassay had a useful range of 10-1000 pmoles.

    In plain wordsIn lab tests, a new thymosin beta‑4 radioimmunoassay worked over a range of 10-1000 pmoles.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    Not applicableRadioimmunoassay working range
    Study

    n: not reported in source

    Radioimmunoassay with rabbit polyclonal antibodies against thymosin beta 4 (1-15)
    Outcome group
    Receptor activity and mechanism · Pharmacology

    Measurements

    useful range
    10 to 1000 pmoles
    radioimmunoassay

    Source sentences

    Summary
    This radioimmunoassay, with a useful range of 10-1000 pmoles, showed cross-reactivity with the second homologous beta-thymosin of man and rat (thymosin beta 10) but not of calf (thymosin beta 9).

    In this study, Thymosin beta-4 (human) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymosin beta-4 (human).

  2. 03LabNot a test of Thymosin beta-4 (human) aloneIn vitro (cell-free)Other

    The thymosin beta‑4 radioimmunoassay cross-reacted with thymosin beta 10 of man and rat but not with thymosin beta 9 of calf.

    In plain wordsIn lab tests, the thymosin beta‑4 assay also detected thymosin beta 10 of man and rat but not thymosin beta 9 of calf.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    Not applicableRadioimmunoassay cross-reactivity with other beta-thymosins
    Study

    n: not reported in source

    Radioimmunoassay with rabbit polyclonal antibodies against thymosin beta 4 (1-15)
    Outcome group
    Receptor activity and mechanism · Pharmacology

    Source sentences

    Summary
    This radioimmunoassay, with a useful range of 10-1000 pmoles, showed cross-reactivity with the second homologous beta-thymosin of man and rat (thymosin beta 10) but not of calf (thymosin beta 9).

    In this study, Thymosin beta-4 (human) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymosin beta-4 (human).

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 01:52 UTC

    Study results updated

  2. Version 1

    12 Oct 2026, 18:17 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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