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Study · Measured the body's own peptide · 1992

5 results

Serum levels of immunoreactive thymosin alpha 1 and thymosin beta 4 in large cohorts of healthy adults.

Weller FE, Shah U, Cummings GD, Chretien PB, Mutchnick MG

Thymus1 Feb 1992Cited by 24 (Europe PMC)

PMID1566283 (opens in a new tab)PepBankPUB-01566283
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study5

No result from this study comes from a test of the peptide.

Natural levels measured5

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01HumanEndogenous levelObservational studyOther

    In 681 healthy adults, serum immunoreactive thymosin alpha‑1 had a geometric mean of 540 pg/ml, with a range of 252 to 1158 pg/ml.

    In plain wordsIn healthy adults, the body's own thymosin alpha‑1 in blood averaged 540 pg/ml.

    Peptide
    Thymosin alpha-1
    Outcome
    Not applicableSerum immunoreactive thymosin alpha 1 level in healthy adults
    Study

    n = 681

    Outcome group
    Endogenous peptide levels · Immune and inflammation

    Measurements

    Serum geometric mean
    540 pg/ml
    healthy adults
    Serum range
    252 to 1158 pg/ml
    healthy adults

    Source sentences

    Summary
    Immunoreactive thymosin alpha 1 was found to occur at a geometric mean of 540 pg/ml with a range from 252 to 1158 pg/ml.
    1 context sentence
    Summary · context
    Enzyme linked immunosorbent assays were used to measure serum levels of immunoreactive thymosin alpha 1 and thymosin beta 4 in 681 healthy adults (range 18 yr-101 yr).

    This result measures the body's own Thymosin alpha-1. Nobody was given the peptide. It is not evidence about taking it.

  2. 02HumanEndogenous levelObservational studyOther

    In healthy adults, serum thymosin alpha‑1 levels did not differ by race, sex or age.

    In plain wordsIn healthy adults, natural thymosin alpha‑1 levels in blood did not differ by race, sex or age.

    Peptide
    Thymosin alpha-1
    Outcome
    No significant changeSerum thymosin alpha 1 by race, sex and age
    Study

    n = 681

    Outcome group
    Endogenous peptide levels · Immune and inflammation

    Source sentences

    Summary
    There were no differences in the levels when analyzed according to race, sex or age.
    1 context sentence
    Summary · context
    Enzyme linked immunosorbent assays were used to measure serum levels of immunoreactive thymosin alpha 1 and thymosin beta 4 in 681 healthy adults (range 18 yr-101 yr).

    This result measures the body's own Thymosin alpha-1. Nobody was given the peptide. It is not evidence about taking it.

  3. 03HumanEndogenous levelObservational studyOther

    In healthy adults, serum immunoreactive thymosin beta‑4 had a geometric mean of 12.6 ng/ml.

    In plain wordsIn healthy adults, the body's own thymosin beta‑4 in blood averaged 12.6 ng/ml.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    Not applicableSerum immunoreactive thymosin beta 4 level
    Study

    n = 681

    Outcome group
    Aging markers · Whole body

    Measurements

    geometric mean
    12.6 ng/ml
    healthy adults
    range
    6.9 to 23 ng/ml
    healthy adults

    Source sentences

    Summary
    Immunoreactive thymosin beta 4 was measured at a geometric mean of 12.6 ng/ml with a range from 6.9 to 23.0 ng/ml.
    1 context sentence
    Summary · context
    Enzyme linked immunosorbent assays were used to measure serum levels of immunoreactive thymosin alpha 1 and thymosin beta 4 in 681 healthy adults (range 18 yr-101 yr).

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

  4. 04HumanEndogenous levelObservational studyOther

    In healthy adults, serum thymosin beta‑4 did not differ by race or sex.

    In plain wordsIn healthy adults, the body's own thymosin beta‑4 levels did not differ by race or sex.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    No significant changeThymosin beta 4 by race and sex
    Study

    n = 681

    Outcome group
    Aging markers · Whole body

    Source sentences

    Summary
    There were no differences in the levels when analyzed according to race or sex
    1 context sentence
    Summary · context
    Enzyme linked immunosorbent assays were used to measure serum levels of immunoreactive thymosin alpha 1 and thymosin beta 4 in 681 healthy adults (range 18 yr-101 yr).

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

  5. 05HumanEndogenous levelObservational studyOther

    In healthy adults, serum thymosin beta‑4 showed a slight upward trend with increasing age.

    In plain wordsIn healthy adults, the body's own thymosin beta‑4 levels rose slightly with age.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    IncreaseThymosin beta 4 with age
    Study

    n = 681

    Outcome group
    Aging markers · Whole body

    Source sentences

    Summary
    there was a slight upward trend with increasing age.
    1 context sentence
    Summary · context
    Enzyme linked immunosorbent assays were used to measure serum levels of immunoreactive thymosin alpha 1 and thymosin beta 4 in 681 healthy adults (range 18 yr-101 yr).

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 4Current

    12 Oct 2026, 18:17 UTC

    Study data updated · source update from Europe PMC

  2. Version 3

    10 Oct 2026, 08:55 UTC

    Study results updated

  3. Version 2

    9 Oct 2026, 03:03 UTC

    Study data updated · source update from Europe PMC

  4. Version 1

    9 Oct 2026, 03:02 UTC

    First added · source update from Europe PMC

Subjects

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