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Study · Animal study (in vivo) · rat · 1992

4 results

Effect of administration of an analog of LHRH on appetitive learning in young and middle-aged female rats.

Nauton P, Giry N, Bruhat MA, Alliot J

Pharmacology, biochemistry, and behavior1 Dec 1992Cited by 5 (Europe PMC)

PMID1475282 (opens in a new tab)DOI10.1016/0091-3057(92)90474-t (opens in a new tab)PepBankPUB-01475282
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

4 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In younger female rats, D-Trp6-LHRH enhanced visual discrimination performance.

    In plain wordsIn younger female rats, D-Trp6-LHRH improved visual discrimination performance.

    Peptide
    Triptorelin (Trelstar, Decapeptyl)
    Outcome
    IncreaseVisual discrimination in younger females
    Study

    ratn: not reported in source

    Young and middle-aged female rats in a T-maze
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Administration of D-Trp6-LHRH enhanced performance during the visual discrimination in younger females and had no action in middle-aged ones, whereas it inhibited ovary function in both groups.
    1 context sentence
    Summary · context
    Our experiments compare T-maze learning in young and middle-aged female rats and study the effect of administration of an analog of LHRH, D-Trp6-LHRH.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In middle-aged female rats, D-Trp6-LHRH had no effect on visual discrimination performance.

    In plain wordsIn middle-aged female rats, D-Trp6-LHRH had no effect on visual discrimination performance.

    Peptide
    Triptorelin (Trelstar, Decapeptyl)
    Outcome
    No significant changeVisual discrimination in middle-aged females
    Study

    ratn: not reported in source

    Young and middle-aged female rats in a T-maze
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Administration of D-Trp6-LHRH enhanced performance during the visual discrimination in younger females and had no action in middle-aged ones, whereas it inhibited ovary function in both groups.
    1 context sentence
    Summary · context
    Our experiments compare T-maze learning in young and middle-aged female rats and study the effect of administration of an analog of LHRH, D-Trp6-LHRH.
  3. 03AnimalAnimal study (in vivo)Efficacy outcome

    In younger female rats, D-Trp6-LHRH inhibited ovarian function.

    In plain wordsIn younger female rats, D-Trp6-LHRH inhibited ovarian function.

    Peptide
    Triptorelin (Trelstar, Decapeptyl)
    Outcome
    DecreaseOvarian function in younger females
    Study

    ratn: not reported in source

    Young and middle-aged female rats in a T-maze
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Administration of D-Trp6-LHRH enhanced performance during the visual discrimination in younger females and had no action in middle-aged ones, whereas it inhibited ovary function in both groups.
    1 context sentence
    Summary · context
    Our experiments compare T-maze learning in young and middle-aged female rats and study the effect of administration of an analog of LHRH, D-Trp6-LHRH.
  4. 04AnimalAnimal study (in vivo)Efficacy outcome

    In middle-aged female rats, D-Trp6-LHRH inhibited ovarian function.

    In plain wordsIn middle-aged female rats, D-Trp6-LHRH inhibited ovarian function.

    Peptide
    Triptorelin (Trelstar, Decapeptyl)
    Outcome
    DecreaseOvarian function in middle-aged females
    Study

    ratn: not reported in source

    Young and middle-aged female rats in a T-maze
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Administration of D-Trp6-LHRH enhanced performance during the visual discrimination in younger females and had no action in middle-aged ones, whereas it inhibited ovary function in both groups.
    1 context sentence
    Summary · context
    Our experiments compare T-maze learning in young and middle-aged female rats and study the effect of administration of an analog of LHRH, D-Trp6-LHRH.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    22 Oct 2026, 02:26 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 18:59 UTC

    First added · source update from Europe PMC

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