A fragment assembly procedure produced calculated local backbone conformations, for myoglobin, lysozyme and thymosin beta‑4, of which substantial fractions were similar to experimentally determined structures.
In plain wordsA computer method predicted parts of protein shapes, including thymosin beta‑4, and many parts matched the shapes found by experiment.
- Peptide
- Thymosin beta-4 (human)
- Outcome
- Not applicableAgreement of calculated local backbone conformations with experimental structures
- Study
n: not reported in source
Knowledge-based fragment assembly model- Outcome group
- Receptor activity and mechanism · Pharmacology
Source sentences
We demonstrate that substantial fractions of the calculated local backbone conformations are similar to the experimentally determined structures.
1 context sentence(design, population, supporting numbers)
The procedure is applied to the calculation of the local backbone conformations of myoglobin and lysozyme whose structures have been solved by X-ray analysis and thymosin beta 4, a polypeptide of 43 amino acid residues whose structure was recently investigated by NMR spectroscopy.
In this study, Thymosin beta-4 (human) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymosin beta-4 (human).