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Study · Animal study (in vivo) · wistar rat · 1976

3 results

[Tumor hyperacidulation through glucose infusion enhanced by nicotinamide adenine dinucleotide (author's transl)].

von Ardenne M, Reitnauer PG

Archiv fur Geschwulstforschung1 Jan 1976Cited by 10 (Europe PMC)

PMID184752 (opens in a new tab)PepBankPUB-00184752
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In tumor-bearing Wistar rats, adding NAD after glucose infusion reportedly increased tumor acidity versus glucose infusion alone.

    In plain wordsIn rats with tumors, adding NAD reportedly increased tumor acidity compared with glucose infusion alone.

    Peptide
    NAD+ (nicotinamide adenine dinucleotide)
    Outcome
    IncreaseTumor acidity after addition of NAD
    Study

    Wistar ratn = 6

    Walker carcinosarcoma 256-bearing rats
    Comparator
    glucose infusion alone
    Outcome group
    Tumor growth · Cancer
    Studied dose
    200 mg NAD in 7 ml 40 per cent. Gk-solution · infusionAs given in this study (Wistar rat).

    Source sentences

    Summary
    Tumor peracidity in Walker carcinosarcoma 256-bearing Wistar rats attained by glucose (Gk) infusion was significantly (t-Test; p = 3.49) increased by a following infusion of 200 mg NAD in 7 ml 40 per cent.
    2 context sentences
    Summary · context
    Gk-solution.
    Summary · context
    The mean pH values obtained on six animals amounted 6.88 (start), 5.21 (after Gk) and 5.79 (after Gk + NAD).
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In tumor-bearing Wistar rats, mean tumor pH was 5.79 after glucose plus NAD versus 5.21 after glucose infusion.

    In plain wordsIn rats with tumors, tumor pH was higher after glucose plus NAD than after glucose alone.

    Peptide
    NAD+ (nicotinamide adenine dinucleotide)
    Outcome
    IncreaseTumor pH after addition of NAD
    Study

    Wistar ratn = 6

    Walker carcinosarcoma 256-bearing rats
    Comparator
    after glucose infusion
    Outcome group
    Tumor growth · Cancer
    Studied dose
    200 mg NAD in 7 ml 40 per cent. Gk-solution · infusionAs given in this study (Wistar rat).

    Measurements

    Mean tumor pH
    5.79 pH
    after Gk + NAD
    Mean tumor pH
    5.21 pH
    after Gk

    Source sentences

    Summary
    The mean pH values obtained on six animals amounted 6.88 (start), 5.21 (after Gk) and 5.79 (after Gk + NAD).

Studies that did not test the peptide alone1

In this study, NAD+ (nicotinamide adenine dinucleotide) was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking NAD+ (nicotinamide adenine dinucleotide).

  1. 03AnimalNot a test of NAD+ (nicotinamide adenine dinucleotide) aloneAnimal study (in vivo)Efficacy outcome

    In tumor-bearing Wistar rats, three animals were cured through the glucose-and-NAD hyperacidification process.

    In plain wordsIn rats with tumors, three animals were cured through the combined glucose-and-NAD hyperacidification process.

    Peptide
    NAD+ (nicotinamide adenine dinucleotide)
    Outcome
    Not applicableCures after hyperacidification
    Study

    Wistar ratn: not reported in source

    Walker carcinosarcoma 256-bearing rats
    Outcome group
    Tumor growth · Cancer

    Source sentences

    Summary
    Three animals were cured through the hyperacidification process.
    1 context sentence
    Summary · context
    Tumor peracidity in Walker carcinosarcoma 256-bearing Wistar rats attained by glucose (Gk) infusion was significantly (t-Test; p = 3.49) increased by a following infusion of 200 mg NAD in 7 ml 40 per cent.

    In this study, NAD+ (nicotinamide adenine dinucleotide) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking NAD+ (nicotinamide adenine dinucleotide).

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    14 Oct 2026, 05:02 UTC

    Study results updated

  2. Version 1

    14 Oct 2026, 01:46 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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