In healthy subjects during somatostatin infusion, glucose production fell from 1.8 +/- 0.2 to 0.9 +/- 0.2 mg/kg . min immediately after glucagon withdrawal.
In plain wordsIn healthy subjects during somatostatin infusion, glucose production fell right after glucagon was withdrawn.
- Peptide
- Glucagon
- Outcome
- DecreaseGlucose production after withdrawal
- Study
n = 6
- Comparator
- Pre-withdrawal period on concomitant glucagon and somatostatin infusion
- Outcome group
- Glycemic control · Metabolic and weight
- Studied dose
- Dose not stated · infusion · 5 hoursAs given in this study (human).
Measurements
- Glucose production
- 1.8 mg/kg . min
- before withdrawal; +/- 0.2
- Glucose production
- 0.9 mg/kg . min
- after withdrawal; +/- 0.2
Source sentences
Glucagon withdrawal at 5 hours produced an immediate decline in Ra from 1.8 +/- 0.2 to 0.9 +/- 0.2 mg/kg . min.
1 context sentence(design, population, supporting numbers)
Six additional subjects received an 8 hour somatostatin infusion, with glucagon administered concomitantly for the first 5 hours.