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Orforglipron clinical trials: 31 trials

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Read 31 Orforglipron clinical trials with posted results or linked papers with results in PepBank.

  1. A Study of Orforglipron (LY3502970) in Adult Participants With Obesity or Overweight With Weight-Related Comorbidities

    NCT05869903 · Phase 3 · Active, not recruiting

    Posted results

  2. A Study of Orforglipron (LY3502970) Compared With Semaglutide in Participants With Type 2 Diabetes Inadequately Controlled With Metformin

    NCT06045221 · Phase 3 · Completed

    Posted results

  3. A Study of Orforglipron in Adult Participants With Obesity or Overweight and Type 2 Diabetes

    NCT05872620 · Phase 3 · Completed

    Posted results

  4. A Study of Orforglipron (LY3502970) in Adult Participants With Type 2 Diabetes and Inadequate Glycemic Control With Diet and Exercise Alone

    NCT05971940 · Phase 3 · Completed

    Posted results

  5. A Study of Orforglipron (LY3502970) in Participants With Type 2 Diabetes and Inadequate Glycemic Control With Insulin Glargine, With or Without Metformin and/or SGLT-2 Inhibitor

    NCT06109311 · Phase 3 · Completed

    Posted results

  6. A Long-term Safety Study of Orforglipron (LY3502970) in Participants With Type 2 Diabetes

    NCT06010004 · Phase 3 · Completed

    Posted results

  7. A Study of Once-Daily Oral Orforglipron (LY3502970) in Japanese Adult Participants With Obesity Disease

    NCT05931380 · Phase 3 · Completed

    Posted results

  8. A Study of Daily Oral Orforglipron (LY3502970) Compared With Insulin Glargine in Participants With Type 2 Diabetes and Obesity or Overweight at Increased Cardiovascular Risk

    NCT05803421 · Phase 3 · Completed

    Linked paper with results

  9. A Study of Orforglipron (LY3502970) Compared With Dapagliflozin in Adult Participants With Type 2 Diabetes and Inadequate Glycemic Control With Metformin

    NCT06192108 · Phase 3 · Completed

    Linked paper with results

  10. A Study of Orforglipron for the Maintenance of Body Weight Reduction in Participants Who Have Obesity or Overweight With Weight-Related Comorbidities (ATTAIN-MAINTAIN)

    NCT06584916 · Phase 3 · Completed

    Linked paper with results

  11. A Study of LY3502970 in Participants With Type 2 Diabetes Mellitus

    NCT05048719 · Phase 2 · Completed

    Posted results

  12. A Study of LY3502970 in Participants With Obesity or Overweight With Weight-related Comorbidities

    NCT05051579 · Phase 2 · Completed

    Posted results

  13. A Study to Compare Tablets and Capsules of Orforglipron (LY3502970) in Healthy Participants Who Are Obese or Overweight

    NCT06440980 · Phase 1 · Completed

    Posted results

  14. A Study of LY3502970 in Healthy Participants

    NCT03929744 · Phase 1 · Completed

    Posted results

  15. A Study of LY3502970 in Healthy Overweight and Obese Participants

    NCT05313802 · Phase 1 · Completed

    Posted results

  16. A Study of LY3502970 in Participants With Type 2 Diabetes

    NCT04426474 · Phase 1 · Completed

    Posted results

  17. A Study of LY3502970 in Japanese Participants With Type 2 Diabetes Mellitus

    NCT05086445 · Phase 1 · Completed

    Posted results

  18. A Multiple Dose Study of LY3502970 in Healthy Overweight and Obese Participants

    NCT05841238 · Phase 1 · Completed

    Posted results

  19. A Drug-Drug Interaction Study of Orforglipron (LY3502970) in Healthy Overweight and Obese Participants

    NCT06186622 · Phase 1 · Completed

    Posted results

  20. A Study of Two Different Formulations of LY3502970 in Healthy Participants

    NCT05341089 · Phase 1 · Completed

    Posted results

  21. A Multiple-Dose Study of LY3502970 in Healthy Participants

    NCT05110794 · Phase 1 · Completed

    Posted results

  22. A Drug Interaction Study of Cyclosporine and LY3502970 in Healthy Participants

    NCT05573230 · Phase 1 · Completed

    Posted results

  23. A Drug-Drug Interaction (DDI) Study of Orforglipron With Carbamazepine in Healthy Participants

    NCT06370728 · Phase 1 · Completed

    Posted results

  24. A Study of LY3502970 in Participants With Impaired and Normal Liver Function

    NCT05882032 · Phase 1 · Completed

    Posted results

  25. A Drug-Drug Interaction Study of Orforglipron (LY3502970) With Quinidine in Healthy Participants

    NCT06704763 · Phase 1 · Completed

    Posted results

  26. A Multiple Dose Study of LY3502970 in Healthy Participants

    NCT05051566 · Phase 1 · Completed

    Posted results

  27. A Drug Interaction Study of Clarithromycin and LY3502970 in Healthy Participants

    NCT05469126 · Phase 1 · Completed

    Posted results

  28. A Study of LY3502970 in Chinese Participants With Obesity or Are Overweight With Weight-related Comorbidities

    NCT06023095 · Phase 1 · Completed

    Posted results

  29. A Phase 1, Parallel, Single-Dose, Open-Label, Single-Period Study of LY3502970 in Participants With Normal Renal Function and Participants With Renal Impairment.

    NCT05936138 · Phase 1 · Completed

    Posted results

  30. A Phase I Study of LY3502970 in Healthy Participants

    NCT06085482 · Phase 1 · Completed

    Posted results

  31. A Study of LY3502970 in Healthy Male Participants

    NCT04680767 · Phase 1 · Completed

    Posted results

How PepBank reports evidence