Open-Label Proof of Concept Study of VP-315 in Basal Cell Carcinoma
Verrica Pharmaceuticals Inc.92 participants1 Feb 2022 to 15 Apr 2024
Basal Cell Carcinoma · Skin Cancer · Cancer of the Skin, Basal Cell · Cancer of the Skin · Carcinoma
In PepBank now:147 peptides, 6 blends and 13 other compounds97,577 study results from 17,383 studies8,473 clinical trialsUpdated
Comparing 2 peptides · Data version 308560
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| Peptide | Conjugate PNC-27 | Synthetic analog LTX-315 | |
|---|---|---|---|
| Identity | |||
| Kind | Conjugate | Synthetic analog | |
| Area | Immune and antimicrobial | Immune and antimicrobial | |
| Evidence | |||
| Amount of evidence | 41 | 142 | |
| Evidence level | Results from animal studies only | Has results from studies in people | |
| Safety | |||
| Safety results | 6 (0 in people) | 6 (5 in people) | |
| Status | |||
| Approval | Not recorded | ||
| Sport (WADA) | |||
| Registered trials | None registered | 7 · 1 active | |
Shared outcomes
From the regulatory data of each peptide.
Outcome groups with study results for at least two of these peptides. Counts include only results from studies that gave the peptide. Bar length is the number of results, on one scale. The bars show how much was studied, not how large an effect was. A peptide with more studies can look stronger here without being stronger. For results, see the randomized results above.
| Outcome group | PNC-27 | LTX-315 |
|---|---|---|
| Tumor growthCancer | 13310 | 3251512 |
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| Receptor activity and mechanismCancer | 2121 | 29326 |
|---|
| Adverse eventsCancer | 624 | 752 |
|---|
| Mitochondrial functionCancer | 11 | 88 |
|---|
For each outcome that two or more peptides have results for: the best result of a single randomized trial, on the same measure (the same kind of number, the same unit). When a trial has several dose arms, the cell shows the highest dose arm. The trials differ in people, length and dose, so a gap between two cells is not proof that one peptide works better.
No outcome has a randomized-trial result on the same measure for two or more of these peptides yet.
Registered trials, ranked by phase (late phases first), then posted results and enrollment. Status is the registry status. Study results come from published studies. Results posted at ClinicalTrials.gov are shown on each trial page.
No registered trial that tests PNC-27 found in ClinicalTrials.gov.
Top 3 of 7 trials, ranked by phase, then posted results and enrollment: 3 completed · 3 with posted results · source ClinicalTrials.gov (opens in a new tab)
Verrica Pharmaceuticals Inc.92 participants1 Feb 2022 to 15 Apr 2024
Basal Cell Carcinoma · Skin Cancer · Cancer of the Skin, Basal Cell · Cancer of the Skin · Carcinoma
Lytix Biopharma AS23 participants5 Nov 2021 to 1 Jul 2025
Advanced Melanoma
Lytix Biopharma AS6 participants28 Dec 2018 to 11 Oct 2021
Soft Tissue Sarcoma