The Potential of Carnosine Supplementation in Optimising Cardiometabolic Health
Monash University40 participantsOct 2016 to est. Jul 2023
Poor Glycemic Control · Cardiovascular Risk Factors · Cognitive Function 1, Social
In PepBank now:147 peptides, 6 blends and 13 other compounds97,577 study results from 17,383 studies8,473 clinical trialsUpdated
Comparing 2 peptides · Data version 308560
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| Peptide | Synthetic analog Matrixyl (palmitoyl pentapeptide-4) | Natural peptide L-carnosine | |
|---|---|---|---|
| Identity | |||
| Kind | Synthetic analog | Natural peptide | |
| Area | Skin and hair | Skin and hair | |
| Evidence | |||
| Amount of evidence | 26 | 1,203 | |
| Evidence level | Has results from studies in people | Has results from studies in people | |
| Safety | |||
| Safety results | 3 (1 in people) | 34 (20 in people) | |
| Status | |||
| Approval | Not recorded | Not recorded | |
| Sport (WADA) | |||
| Registered trials | None registered | 2 | |
Shared outcomes
From the regulatory data of each peptide.
Outcome groups with study results for at least two of these peptides. Counts include only results from studies that gave the peptide. Bar length is the number of results, on one scale. The bars show how much was studied, not how large an effect was. A peptide with more studies can look stronger here without being stronger. For results, see the randomized results above.
| Outcome group | Matrixyl (palmitoyl pentapeptide-4) | L-carnosine |
|---|---|---|
| Inflammation markersSkin and wound | 11 | 9714794 |
| Adverse events |
PepBank is a research reference. Talk to a doctor before you use any peptide.
312 |
251681 |
| Skin and hairSkin and wound | 1156 | 33 |
|---|
| Wound healingSkin and wound | 1192 | 55 |
|---|
Registered trials, ranked by phase (late phases first), then posted results and enrollment. Status is the registry status. Study results come from published studies. Results posted at ClinicalTrials.gov are shown on each trial page.
No registered trial that tests Matrixyl (palmitoyl pentapeptide-4) found in ClinicalTrials.gov.
2 trials · 1 completed · 1 with posted results · source ClinicalTrials.gov (opens in a new tab)
Monash University40 participantsOct 2016 to est. Jul 2023
Poor Glycemic Control · Cardiovascular Risk Factors · Cognitive Function 1, Social
University of Louisville299 participants1 Apr 2018 to 1 Nov 2022
Air Pollution Toxicity
For each outcome that two or more peptides have results for: the best result of a single randomized trial, on the same measure (the same kind of number, the same unit). When a trial has several dose arms, the cell shows the highest dose arm. The trials differ in people, length and dose, so a gap between two cells is not proof that one peptide works better.
No outcome has a randomized-trial result on the same measure for two or more of these peptides yet.
The other peptides have no randomized result on the same measure, so these results cannot be set side by side.
| Outcome | Matrixyl (palmitoyl pentapeptide-4) | L-carnosine |
|---|---|---|
| Adverse eventsSkin and woundCompared as: value in the arm that got the peptide, in % | No comparable result 1 randomized-trial result measure it in another way or another unit. | 30% Adverse events Placebo: 14% Dose studied: 2 g/day3 monthsn = 752012 |
No comparable result
1 randomized-trial result measure it in another way or another unit.
30%
Adverse events
Placebo: 14%
Dose studied: 2 g/day3 monthsn = 752012