Trial · Interventional
RecruitingPhase 2Registry dataMelanotan II (MT-II) as an Adjunct to NB-UVB Phototherapy for Repigmentation in Stable Nonsegmental Vitiligo
Short name MTII-VIT
Overview
- Status
- Recruiting
- Phase
- Phase 2
- Enrollment
- 60 participants (estimated)
- Sponsor
- Hudson Biotech · Industry
- Design
- Randomized · Quadruple masking
- Countries
1 country
China
- Start
- 2 Feb 2026
- Primary completion
- 14 Feb 2027 (estimated)
- Completion
- 17 Feb 2028 (estimated)
- First posted
- 27 Feb 2026
- Last update posted
- 27 Feb 2026
- Conditions
- NonSegmental Vitiligo · Nonsegmental Vitiligo (Stable)
Timeline
1 trial · 1 ongoing
- Completed
- Ongoing
- Not yet recruiting
- Stopped
- Estimated dates (est.)
- Results posted
- Ph 2
Registry summary
Text and fields below are the sponsor's entries at ClinicalTrials.gov, shown as posted.
This example interventional study record describes a randomized Phase 2 clinical trial evaluating investigational Melanotan II (MT-II) as an adjunct to standard NB-UVB phototherapy for repigmentation in adults with stable nonsegmental vitiligo.
Interventions
- Melanotan II (MT-II)Drug
- PlaceboDrug
- Narrowband UV-B (NB-UVB) phototherapyProcedure
Arms2
Experimental
Melanotan II + NB-UVB phototherapy
Placebo comparator
Placebo + NB-UVB phototherapy
Primary outcomes1
Outcomes the sponsor listed as primary.
Change from baseline in Vitiligo Area Scoring Index (VASI) total score
Time frame · 24 Weeks
Secondary outcomes(1)
Proportion of participants achieving
Time frame · 24 Weeks
Registry description
50% improvement in VASI (VASI50). 2) Time to first clinically detectable repigmentation in target lesions (standardized photography). 3) Change from baseline in objective pigmentation (melanin index) in predefined target lesions (colorimetry). 4) Change from baseline in Dermatology Life Quality Index (DLQI). 5) Incidence and severity of adverse events (AEs) and clinically significant dermatologic changes
Posted results
Values are shown as posted at ClinicalTrials.gov, with their units. PepBank has not converted, pooled or compared them.
No results are posted for this trial.
A trial that is still running, or that stopped early, may post results later.
Registry data comes from ClinicalTrials.gov. Study results come from studies, not from the registry. How PepBank works
Studies0
Studies that cite this trial.
No study cites this trial.
Eligibility
Who could join, as posted.
- Sex
- All
- Age
- from 18 Years up to 65 Years
- Healthy volunteers
- Not accepted
Inclusion and exclusion criteria, as posted
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