Skip to content

Trial · Interventional

RecruitingPhase 1/2Registry data

Efficacy of Prednisolone Versus Cerebrolysin in the Treatment of Bell's Palsy

NCTNCT05821075 (opens ClinicalTrials.gov in a new tab)Other idPRC-Ph-2211038
Open at ClinicalTrials.govAsk about this trial

Overview

Status
Recruiting
Phase
Phase 1/2
Enrollment
90 participants (estimated)
Sponsor
October 6 University · Other
Design
Randomized · Double masking
Countries
1 country

Egypt

Start
24 Aug 2023
Primary completion
Jan 2026 (estimated)
Completion
Feb 2026 (estimated)
First posted
20 Apr 2023
Last update posted
31 Jul 2025
Conditions
Bell Palsy

Timeline

1 trial · 1 ongoing

  • Completed
  • Ongoing
  • Not yet recruiting
  • Stopped
  • Estimated dates (est.)
  • Results posted
20232024202520262027
  1. Ph 1/2

    Efficacy of Prednisolone Versus Cerebrolysin in the Treatment of Bell's Palsy

    NCT05821075

    24 Aug 2023 to est. Feb 2026

Registry summary

Text and fields below are the sponsor's entries at ClinicalTrials.gov, shown as posted.

Bell's palsy, a peripheral facial nerve paresis, is the most common disorder of the facial nerve and one of the most common mononeuropathies. Many patients with Bell's palsy will develop some complications such as synkinesis, crocodile tears and 'sweating' of the ear while eating Commonly used medications to treat Bell's palsy is Corticosteroids Cerebrolysin stimulates the regeneration of the nervous tissue with protective action we aim to study the efficacy of cerebrolycin in Bell's palsy

Interventions

  • PrednisoloneDrug
  • CerebrolysinDrug

Arms3

  • Active comparator

    Prednisolone

  • Active comparator

    Cerebrolysin

  • Active comparator

    Prednisolone and Cerebrolysin

Primary outcomes2

Outcomes the sponsor listed as primary.

  1. change in scores of the house Brackman grading system HB

    Time frame · at baseline, after 1 week, after 3 week

  2. changes in scores of the Sunnybrook grading system.

    Time frame · at baseline, after 1 week, after 3 week

Posted results

Values are shown as posted at ClinicalTrials.gov, with their units. PepBank has not converted, pooled or compared them.

No results are posted for this trial.

A trial that is still running, or that stopped early, may post results later.

Registry data comes from ClinicalTrials.gov. Study results come from studies, not from the registry. How PepBank works

Studies0

Studies that cite this trial.

No study cites this trial.

Eligibility

Who could join, as posted.

Sex
All
Age
from 18 Years up to 60 Years
Healthy volunteers
Not accepted
Inclusion and exclusion criteria, as posted
Inclusion Criteria: * unilateral acute facial palsy of no identifiable cause Exclusion Criteria: * Recurrent facial Bell's palsy * Pregnancy * Diabetes * Epilepsy * Severe hypertension, * Renal or hepatic disease, * Gastric or duodenal ulcer * presence of acute otitis media or ipsilateral chronic otitis * Recent head injury, * psychiatric disease * If there is any contraindications for corticosteroids

PepBank is a research reference. Talk to a doctor before you use any peptide.