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Study · In vitro (cells) · s. aureus and c. albicans · 2002

2 results

Antimicrobial amino acid sequences derived from alpha-melanocyte-stimulating hormone

CATANIA ANNA PIA, LIPTON JAMES M

Journal not recorded21 Sept 2001

PepBankPUB-97781042
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

1 result from studies that gave the peptide. No result from this study comes from people.

  1. 01LabIn vitro (cells)Activity measurement

    The alpha-MSH (11-13) fragment, KPV, was among the most effective antimicrobial peptides tested, with alpha-MSH (1-13) and (6-13).

    In plain wordsIn lab tests, KPV was one of the most effective of the alpha-MSH peptides against microbes.

    Peptide
    KPV
    Outcome
    Not applicableAntimicrobial potency of alpha-MSH (11-13)
    Study

    S. aureus; C. albicansn: not reported in source

    microbial culture
    Outcome group
    Infection and antimicrobial activity · Infection
    Studied dose
    Dose not stated

    Source sentences

    Summary
    The most effective of the peptides were those bearing the C-terminal amino acid sequence of alpha-MSH, i.e., alpha-MSH (1-13), (6-13), and (11-13).

Studies that did not test the peptide alone1

In this study, KPV was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking KPV.

  1. 02LabNot a test of KPV aloneIn vitro (cells)Activity measurement

    Pooled alpha-MSH derived peptides, including KPV-containing sequences, had antimicrobial effects against S. aureus and reduced C. albicans viability.

    In plain wordsIn lab tests, a group of alpha-MSH derived peptides acted against two microbes. The result is for the group, not for KPV alone.

    Peptide
    KPV
    Outcome
    Not applicableAntimicrobial effects against S. aureus and C. albicans
    Study

    S. aureus; C. albicansn: not reported in source

    microbial culture
    Outcome group
    Infection and antimicrobial activity · Infection

    Source sentences

    Summary
    The antimicrobial agent is selected from the group consisting of one or more peptides including the amino acid sequence KPV, one or more peptides including the amino acid sequence MEHFRWG, or a biologically functional equivalent of any of the foregoing.
    1 context sentence
    Summary · context
    alpha-MSH peptides had antimicrobial effects against S. aureus and significantly reversed the enhancing effect of urokinase on S. aureus colony formation. alpha-MSH and other amino acid sequences reduced C. albicans viability and germination.

    In this study, KPV was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking KPV.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    10 Oct 2026, 08:19 UTC

    Study results updated

  2. Version 2

    9 Oct 2026, 03:03 UTC

    Study data updated · source update from Europe PMC

  3. Version 1

    9 Oct 2026, 02:56 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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