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Study · Not a test of the peptide alone · 1997

2 results

Solid phase process for synthesizing thymosin alpha 1

WANG SU S

Journal not recorded15 Apr 1991

PepBankPUB-91520433
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone2

In this study, Thymosin alpha-1 was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Thymosin alpha-1.

  1. 01LabNot a test of Thymosin alpha-1 aloneIn vitro (cell-free)Other

    In solid-phase synthesis of thymosin alpha‑1, the Moz group was removed rapidly and completely with 5-10% trifluoroacetic acid in CH2Cl2.

    In plain wordsIn lab chemistry, a protecting group used to make thymosin alpha‑1 was removed quickly and fully with dilute acid.

    Peptide
    Thymosin alpha-1
    Outcome
    Not applicableRemoval of Moz protecting group
    Study

    n: not reported in source

    solid-phase peptide synthesis
    Outcome group
    Synthesis and manufacturing · Pharmacology

    Source sentences

    Summary
    It was found that the Moz group can be removed rapidly and completely with 5-10% trifluoroacetic acid in CH2Cl2.
    1 context sentence
    Summary · context
    4-methyloxybenzyloxycarbonyl (Moz) is used to protect the alpha amino groups of the amino acids used in solid-phase synthesis of thymosin alpha 1.

    In this study, Thymosin alpha-1 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymosin alpha-1.

  2. 02LabNot a test of Thymosin alpha-1 aloneIn vitro (cell-free)Other

    In solid-phase synthesis of thymosin alpha‑1, Moz-amino acids gave higher yields and purities than Boc-amino acids, with reduced trifluoroacetic acid use.

    In plain wordsIn lab chemistry, a different protecting group gave higher yields and purity than the older one when making thymosin alpha‑1.

    Peptide
    Thymosin alpha-1
    Outcome
    IncreaseSynthesis yield and purity with Moz-amino acids
    Study

    n: not reported in source

    solid-phase peptide synthesis
    Comparator
    Boc-amino acids
    Outcome group
    Synthesis and manufacturing · Pharmacology

    Source sentences

    Summary
    Some advantages of utilizing Moz-amino acids over Boc-amino acids in solid-phase peptide synthesis are higher yields and purities with reduced consumption of trifluoroacetic acid during the acidolytic cleavage of the N alpha -Moz groups.
    1 context sentence
    Summary · context
    4-methyloxybenzyloxycarbonyl (Moz) is used to protect the alpha amino groups of the amino acids used in solid-phase synthesis of thymosin alpha 1.

    In this study, Thymosin alpha-1 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymosin alpha-1.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    10 Oct 2026, 08:55 UTC

    Study results updated

  2. Version 2

    9 Oct 2026, 03:03 UTC

    Study data updated · source update from Europe PMC

  3. Version 1

    9 Oct 2026, 03:02 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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