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Study · Ex vivo tissue · mouse · 2001

2 results

Cloning, expression of thymosin Alpha 1 gene in E. coli and its purification and characterization

Shi Jihong, Zhang Yingqi, Zhao Yongtong, Zhao Ning, Zhu Baoe, Yan Zhen, Han Wei

Zhongguo sheng wu hua xue yu fen zi sheng wu xue bao = Chinese journal of biochemistry and molecular biology1 Jan 2001

PepBankPUB-91245699
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Summary

The text of this summary is not shown here, because the article license does not allow reuse.

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01LabEx vivo tissueActivity measurement

    In mouse spleen lymphocytes, recombinant thymosin alpha‑1 and its fusion protein had biological activity similar to synthesized thymosin alpha‑1.

    In plain wordsIn lab tests on mouse cells, lab-made thymosin alpha‑1 worked about as well as the synthetic form.

    Outcome
    No significant changeBiological activity versus synthesized thymosin alpha 1
    Study

    mousen: not reported in source

    ConA-stimulated spleen lymphocytes
    Comparator
    Synthesized thymosin alpha 1
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    Dose not stated

    Source sentences

    Summary
    The results showed that the fusion protein and Talpha_(1) have the similar biological activity to that of the synthesized Talpha_(1).
  2. 02LabEx vivo tissueActivity measurement

    In ConA-stimulated mouse spleen lymphocytes, recombinant thymosin alpha‑1 and its fusion protein increased proliferative responses.

    In plain wordsIn lab tests on mouse cells, lab-made thymosin alpha‑1 increased immune cell growth.

    Outcome
    IncreaseProliferation of ConA-stimulated spleen lymphocytes
    Study

    mousen: not reported in source

    ConA-stimulated spleen lymphocytes
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    Dose not stated

    Source sentences

    Summary
    They could increase the proliferative responses of the mitogen ConA stimulated mice spleen lymphocytes.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    12 Oct 2026, 17:28 UTC

    Study results updated

  2. Version 2

    9 Oct 2026, 03:03 UTC

    Study data updated · source update from Europe PMC

  3. Version 1

    9 Oct 2026, 03:02 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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