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Study · Animal study (in vivo) · oreochromis sp. · 2016

6 results

Oral administration of the growth hormone secretagogue-6 (GHRP-6) enhances growth and non-specific immune responses in tilapia (Oreochromis sp.)

Martinez R, Carpio Y, Morales A, Lugo JM, Herrera F, Zaldívar C, Carrillo O, Arenal A, Pimentel E, Estrada MP

Aquaculture.1 Feb 2016Cited by 12 (Europe PMC)

DOI10.1016/j.aquaculture.2015.11.014 (opens in a new tab)PepBankPUB-91144856
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study6

6 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In juvenile tilapia, GHRP‑6 induced liver insulin growth factor-I messenger RNA.

    In plain wordsIn tilapia, GHRP‑6 increased liver insulin growth factor-I gene activity.

    Peptide
    GHRP-6
    Outcome
    IncreaseLiver IGF-I mRNA
    Study

    Oreochromis sp.n: not reported in source

    Tilapia
    Outcome group
    Growth hormone and IGF-1 · Endocrine and hormones
    Studied dose
    Dose not stated · intraperitonealAs given in this study (Oreochromis sp.).

    Source sentences

    Summary
    In the present study, we demonstrate that intraperitoneal administration of GHRP-6 induces liver insulin growth factor-I messenger RNA, and increases growth hormone levels in juvenile tilapia (Oreochromis sp.), in a time-course experiment.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In juvenile tilapia, GHRP‑6 increased growth hormone levels.

    In plain wordsIn tilapia, GHRP‑6 increased growth hormone levels.

    Peptide
    GHRP-6
    Outcome
    IncreaseGrowth hormone levels
    Study

    Oreochromis sp.n: not reported in source

    Tilapia
    Outcome group
    Growth hormone and IGF-1 · Endocrine and hormones
    Studied dose
    Dose not stated · intraperitonealAs given in this study (Oreochromis sp.).

    Source sentences

    Summary
    In the present study, we demonstrate that intraperitoneal administration of GHRP-6 induces liver insulin growth factor-I messenger RNA, and increases growth hormone levels in juvenile tilapia (Oreochromis sp.), in a time-course experiment.
  3. 03AnimalAnimal study (in vivo)Efficacy outcome

    In juvenile tilapia, non-encapsulated and encapsulated GHRP‑6 stimulated growth after pharyngeal administration.

    In plain wordsIn tilapia, both non-encapsulated and encapsulated GHRP‑6 stimulated growth.

    Peptide
    GHRP-6
    Outcome
    IncreaseJuvenile growth
    Study

    Oreochromis sp.n: not reported in source

    Tilapia
    Outcome group
    Body weight · Whole body
    Studied dose
    Dose not stated · pharyngeal cavity via plastic tubeAs given in this study (Oreochromis sp.).

    Source sentences

    Summary
    GHRP-6 also stimulates growth using non-encapsulated and encapsulated peptide administered by a plastic tube to the pharyngeal cavity to juveniles.
  4. 04AnimalAnimal study (in vivo)Efficacy outcome

    In tilapia larvae, GHRP‑6 in formulated feed increased growth.

    In plain wordsIn tilapia larvae, GHRP‑6 in feed increased growth.

    Peptide
    GHRP-6
    Outcome
    IncreaseLarval growth
    Study

    Oreochromis sp.n: not reported in source

    Tilapia
    Outcome group
    Body weight · Whole body
    Studied dose
    Dose not stated · formulated feedAs given in this study (Oreochromis sp.).

    Source sentences

    Summary
    Growth and immune parameters such as lectin titers and intestinal intraepithelial lymphocyte numbers were increased in treated larvae.
    1 context sentence
    Summary · context
    In addition, administration of GHRP-6 in formulated feed to tilapia larvae was assessed.
  5. 05AnimalAnimal study (in vivo)Efficacy outcome

    In tilapia larvae, GHRP‑6 treatment increased lectin titers.

    In plain wordsIn tilapia larvae, GHRP‑6 increased lectin titers.

    Peptide
    GHRP-6
    Outcome
    IncreaseLectin titers
    Study

    Oreochromis sp.n: not reported in source

    Tilapia
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    Dose not stated · formulated feedAs given in this study (Oreochromis sp.).

    Source sentences

    Summary
    Growth and immune parameters such as lectin titers and intestinal intraepithelial lymphocyte numbers were increased in treated larvae.
    1 context sentence
    Summary · context
    In addition, administration of GHRP-6 in formulated feed to tilapia larvae was assessed.
  6. 06AnimalAnimal study (in vivo)Efficacy outcome

    In tilapia larvae, GHRP‑6 treatment increased intestinal intraepithelial lymphocyte numbers.

    In plain wordsIn tilapia larvae, GHRP‑6 increased immune cell numbers in the intestinal lining.

    Peptide
    GHRP-6
    Outcome
    IncreaseIntestinal intraepithelial lymphocyte numbers
    Study

    Oreochromis sp.n: not reported in source

    Tilapia
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    Dose not stated · formulated feedAs given in this study (Oreochromis sp.).

    Source sentences

    Summary
    Growth and immune parameters such as lectin titers and intestinal intraepithelial lymphocyte numbers were increased in treated larvae.
    1 context sentence
    Summary · context
    In addition, administration of GHRP-6 in formulated feed to tilapia larvae was assessed.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    21 Oct 2026, 15:58 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:13 UTC

    First added · source update from Europe PMC

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