Study · Animal study (in vivo) · mouse · 2026
2 resultsYang Y, Chen H, Xiang S, Wei Y, Zhang L, Sun A, E X, Wu F, Luo N, Liang F, Wu X, Wang C and 14 more
Chen Z, Zhang Q, Chen X, Wu Q, Han Z, Li C, Yin R, Ren G, Li J, Zhao K, Gao H, Wang R, Yu M, Yang X
Signal transduction and targeted therapy15 Sept 2026
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Text rights: CC BY-NC-ND. Results still quote short attributed sentences.
2 results from studies that gave the peptide. No result from this study comes from people.
In aged HPS-knockout mice, AICAR ameliorated the liver aging phenotype.
In plain wordsIn aged mice without HPS, AICAR reduced signs of liver aging.
mousen: not reported in source
Aged HPS-knockout miceSource sentences
Treatment with the AMPK agonist AICAR ameliorated the liver aging phenotype and restored liver regenerative capacity in aged HPS-KO mice.
In aged HPS-knockout mice, AICAR restored liver regenerative capacity.
In plain wordsIn aged mice without HPS, AICAR restored the liver's ability to regenerate.
mousen: not reported in source
Aged HPS-knockout miceSource sentences
Treatment with the AMPK agonist AICAR ameliorated the liver aging phenotype and restored liver regenerative capacity in aged HPS-KO mice.
AI wrote and checked these results. AI can make mistakes, so check important results against the source.
PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.
Version 2Current
21 Oct 2026, 15:58 UTC
Study results updated
Version 1
21 Oct 2026, 12:50 UTC
First added · source update from Europe PMC
Terms as the source lists them.
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In PepBank now:147 peptides, 6 blends and 13 other compounds97,577 study results from 17,383 studies8,473 clinical trialsUpdated