In healthy adults, Bifidobacterium infantis BI45 supplementation significantly increased serum levels of the body's own LL‑37 versus placebo.
In plain wordsIn healthy adults, a probiotic raised the body's own LL‑37 level in blood more than placebo did.
- Peptide
- LL-37
- Outcome
- IncreaseSerum LL-37 level
- Study
n = 48
- Comparator
- Placebo
- Outcome group
- Immune response · Immune and inflammation
Source sentences
B. infantis BI45 supplementation significantly increased serum levels of immunomodulatory markers Immunoglobulin A (IgA) and antimicrobial peptide LL-37 compared to the placebo (p < 0.05)
1 context sentence(design, population, supporting numbers)
Forty-eight healthy adults were recruited and randomly assigned to receive either B. infantis BI45 or a placebo (n = 24/group) for 8 weeks.
This result measures the body's own LL-37. Nobody was given the peptide. It is not evidence about taking it.