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Study · Other design · 2026

2 results

Kaempferol alleviates right ventricular hypertrophy in high-altitude pulmonary hypertension rats by modulating the AMPK/ACC/CPT1B axis and the AMPK-mediated LDHA/PDHA1 pathway.

Zhao Q, Su S, Chen J, Huayu M, Nan X, Li X, Li Z, Lu D

Food & function14 Apr 2026

PMID41804727 (opens in a new tab)DOI10.1039/d5fo04265h (opens in a new tab)PepBankPUB-41804727
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01LabOther designMechanism

    AICAR co-treatment partially reversed kaempferol's effects on AMPK-mediated glucose oxidation in the experimental model.

    In plain wordsIn lab tests, AICAR partly reversed kaempferol's effect on glucose oxidation compared with kaempferol alone.

    Peptide
    AICAR (acadesine)
    Outcome
    Direction not reportedGlucose oxidation
    Study

    n: not reported in source

    Comparator
    Kaempferol alone
    Outcome group
    Receptor activity and mechanism · Cardiovascular
    Studied dose
    Dose not stated

    Source sentences

    Summary
    The effects of kaempferol on AMPK-mediated glucose and fatty acid oxidation were partially reversed by AICAR co-treatment, confirming the involvement of the AMPK pathway.
  2. 02LabOther designMechanism

    AICAR co-treatment partially reversed kaempferol's effects on AMPK-mediated fatty acid oxidation in the experimental model.

    In plain wordsIn lab tests, AICAR partly reversed kaempferol's effect on fatty acid oxidation compared with kaempferol alone.

    Peptide
    AICAR (acadesine)
    Outcome
    Direction not reportedFatty acid oxidation
    Study

    n: not reported in source

    Comparator
    Kaempferol alone
    Outcome group
    Receptor activity and mechanism · Cardiovascular
    Studied dose
    Dose not stated

    Source sentences

    Summary
    The effects of kaempferol on AMPK-mediated glucose and fatty acid oxidation were partially reversed by AICAR co-treatment, confirming the involvement of the AMPK pathway.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    21 Oct 2026, 15:58 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 12:50 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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