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Study · Animal study (in vivo) · cynomolgus monkey · 2026

2 results

Diurnal and Daily Variations in Growth Hormone and Growth Hormone Stimulation Test in Male Cynomolgus Monkeys.

Taniguchi Y, Yoshikawa T, Yamada T, Kawaguchi H

In vivo (Athens, Greece)1 Jan 2026

PMID41482410 (opens in a new tab)PMCIDPMC12764231 (opens in a new tab)DOI10.21873/invivo.14182 (opens in a new tab)PepBankPUB-41482410
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: CC BY-NC-ND. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Activity measurement

    In adult male cynomolgus monkeys, intravenous pralmorelin gave higher serum GH at 0.5 h than saline (p<0.05).

    In plain wordsIn monkeys, pralmorelin raised growth hormone at 30 minutes more than saline.

    Peptide
    GHRP-2
    Outcome
    IncreaseSerum GH at 0.5 h
    Study

    cynomolgus monkeyn = 8

    Adult male cynomolgus monkeys, GH stimulation test
    Comparator
    Physiological saline
    Outcome group
    Growth hormone and IGF-1 · Endocrine and hormones
    Studied dose
    Dose not stated · intravenousAs given in this study (cynomolgus monkey).

    Measurements

    p value
    < 0.05
    GH at 0.5 h

    Source sentences

    Summary
    In the stimulation test, compared to the control group, the GHRH group showed higher GH concentrations at 0.5 h (pp<0.05).
    1 context sentence
    Summary · context
    In the GH stimulation test, four animals received intravenous pralmorelin hydrochloride (as GHRH) and four received physiological saline between 11:00 and 11:30.
  2. 02AnimalAnimal study (in vivo)Activity measurement

    In adult male cynomolgus monkeys, intravenous pralmorelin gave a greater GH area under the curve than saline (p<0.05).

    In plain wordsIn monkeys, pralmorelin raised total growth hormone exposure more than saline.

    Peptide
    GHRP-2
    Outcome
    IncreaseGH area under the curve
    Study

    cynomolgus monkeyn = 8

    Adult male cynomolgus monkeys, GH stimulation test
    Comparator
    Physiological saline
    Outcome group
    Growth hormone and IGF-1 · Endocrine and hormones
    Studied dose
    Dose not stated · intravenousAs given in this study (cynomolgus monkey).

    Measurements

    p value
    < 0.05
    GH AUC

    Source sentences

    Summary
    In the stimulation test, compared to the control group, the GHRH group showed higher GH concentrations at 0.5 h (pp<0.05).
    1 context sentence
    Summary · context
    In the GH stimulation test, four animals received intravenous pralmorelin hydrochloride (as GHRH) and four received physiological saline between 11:00 and 11:30.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 21:44 UTC

    Study results updated

  2. Version 1

    13 Oct 2026, 16:31 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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