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Study · Observational study · 2025

1 result

Survey of Drugs Induced Skin Pigmentation (Hyper and Hypo Pigmentation).

Tang J, Lv B, Liu L, Hu Y, Li K, Xu L, Zheng J, Liu G, Jiao L, Li Q

Clinical, cosmetic and investigational dermatology17 Nov 2025

PMID41281582 (opens in a new tab)PMCIDPMC12638260 (opens in a new tab)DOI10.2147/ccid.s557919 (opens in a new tab)PepBankPUB-41281582
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: CC BY-NC. Results still quote short attributed sentences.

Results from this study1

1 result from studies that gave the peptide. 1 result from people.

  1. 01HumanObservational studySafety outcome

    In FAERS reports, setmelanotide was associated with hyperpigmentation with a reporting odds ratio of 1506.82.

    In plain wordsIn adverse event reports, setmelanotide was linked to disproportionately frequent reports of darker skin.

    Peptide
    Setmelanotide
    Outcome
    IncreaseHyperpigmentation reporting odds ratio
    Study

    n: not reported in source

    Outcome group
    Pigmentation · Skin and wound
    Studied dose
    Dose not stated

    Measurements

    Reporting odds ratio
    1506.82 ratio
    Hyperpigmentation

    Source sentences

    Summary
    Minocycline (ROR 115.66) and setmelanotide (ROR 1506.82) showed high RORs for hyperpigmentation,
    2 context sentences
    Summary · context
    The study analyzed case reports from the FAERS database using the OpenVigil 2.1 platform.
    Summary · context
    Disproportionality analysis was performed using the Reporting Odds Ratio (ROR) to detect significant associations between drugs and pigmentary AEs.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    28 Oct 2026, 02:03 UTC

    Study results updated

  2. Version 1

    27 Oct 2026, 16:36 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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