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Study · Randomized controlled trial · 2026

1 result

Linaclotide in combination with compound polyethylene glycol powder enhances bowel preparation for colonoscopy in patients aged over 60 years: a multi-center, endoscopist-blind, randomized controlled trial.

Sun W, Zhao L, Ran Y, Zhao W, Zhang L, Xiao J, Peng Y, Zhang Z, Dong M, Xiang S, Wu K

Scandinavian journal of gastroenterology12 Nov 2025

PMID41222080 (opens in a new tab)DOI10.1080/00365521.2025.2588230 (opens in a new tab)PepBankPUB-41222080
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

1 result from studies that gave the peptide. 1 result from people.

  1. 01HumanRandomized controlled trialEfficacy outcome

    In patients over 60, linaclotide plus 2 L PEG had superior BBPS scores, preparation rates and intubation time versus 2 L PEG.

    In plain wordsIn patients over 60, linaclotide plus 2 L PEG improved the reported preparation measures versus 2 L PEG.

    Peptide
    Linaclotide
    Outcome
    Direction not reportedBBPS score, adequate preparation rate and cecal intubation time
    Study

    n: not reported in source

    Comparator
    2 L PEG
    Outcome group
    Bowel Preparation · Gastrointestinal
    Studied dose
    Dose not stated

    Source sentences

    Summary
    The total BBPS scores, ABPR and CIT in the Lina + 2 L-PEG group and the 3 L-PEG group were superior to those in the 2 L-PEG group(p < 0.05).
    2 context sentences
    Summary · context
    A multi-center, endoscopist-blind, randomized controlled trial involved 527 patients aged over 60 years scheduled for colonoscopy at two hospitals in Chongqing from January 2022 to December 2023.
    Summary · context
    Participants were randomly assigned to one of three groups: Lina + 2 litres of PEG (L-PEG), 3 L-PEG, or 2 L-PEG.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    28 Oct 2026, 02:03 UTC

    Study results updated

  2. Version 1

    27 Oct 2026, 16:34 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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