In heterologous and homologous expressing cells, the FLARE-MC sensor responded with high potency and selectivity to the synthetic melanocortin agonist MTII.
In plain wordsIn cells, a new melanocortin sensor responded strongly and selectively to MTII, which was used as a test agonist.
- Peptide
- Melanotan II
- Outcome
- Not applicableFLARE-MC sensor response to MTII
- Study
n: not reported in source
Cells expressing the FLARE-MC sensor- Outcome group
- Receptor activity and mechanism · Pharmacology
Source sentences
The FLAREMC sensor has high potency and selectivity in heterologous and homologous expressing cells for α-MSH and the synthetic melanocortin agonist MTII but not to the inverse agonist AgRP.
In this study, Melanotan II was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Melanotan II.