Skip to content

Study · In vitro (cells) · 2025

1 result

Glycyrrhizin alleviates contrast-induced acute kidney injury via inhibiting HMGB1-mediated renal tubular epithelial cells ferroptosis.

Tian FY, Liu K, Tang ZY, Zhou G, Zhou GL, Chen RF, Liu HB, Fang WJ, Zuo XC, Zhou LY

Renal failure31 Aug 2025Cited by 8 (Europe PMC)

PMID40887103 (opens in a new tab)PMCIDPMC12404086 (opens in a new tab)DOI10.1080/0886022x.2025.2548613 (opens in a new tab)PepBankPUB-40887103
Read at sourcePubMedAsk about this study
Jump to 1 result

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: CC BY-NC. Results still quote short attributed sentences.

Results from this study1

1 result from studies that gave the peptide. No result from this study comes from people.

  1. 01LabIn vitro (cells)Mechanism

    In renal tubular cell experiments, AICAR produced results described as comparable, without a distinct endpoint result being specified.

    In plain wordsIn lab tests, AICAR produced comparable results, but the abstract does not specify a distinct result.

    Peptide
    AICAR (acadesine)
    Outcome
    Direction not reportedComparable in vitro results
    Study

    n: not reported in source

    iohexol-treated renal tubular epithelial cells
    Outcome group
    Receptor activity and mechanism · Kidney and urinary
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Comparable results were obtained in vitro with AICAR treatment.
    1 context sentence
    Summary · context
    HMGB1 silencing was able to inhibit overactivation of AMPK/Beclin-1 axis during CI-AKI, and iohexol-downregulated protein expressions of GPX4 and SLC7A11 were reversed in kidneys of AMPK knockout mice.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    21 Oct 2026, 15:58 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 12:50 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

PepBank is a research reference. Talk to a doctor before you use any peptide.