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Study · Measured the body's own peptide · 2025

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Key Factors Influencing Caries Development in Preschoolers: A Focus on Socio-Demographic, Maternal Health, and Salivary Biomarkers in 3-Year-Olds.

Stojkovic B, Igic M, Jevtovic Stoimenov T, Trickovic Janjic O, Ignjatovic A, Kostic M, Stojanovic S, Petrovic M, Stojanovic A, Velickovic Z

Medical science monitor : international medical journal of experimental and clinical research29 Jun 2025

PMID40581810 (opens in a new tab)PMCIDPMC12224950 (opens in a new tab)DOI10.12659/msm.948857 (opens in a new tab)PepBankPUB-40581810
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: CC BY-NC-ND. Results still quote short attributed sentences.

Results from this study1

No result from this study comes from a test of the peptide.

Natural levels measured1

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01HumanEndogenous levelObservational studyOther

    In 3-year-old children, salivary LL‑37 levels showed no caries-predictive significance over one year.

    In plain wordsIn 3-year-olds, natural LL‑37 levels in saliva did not predict who developed cavities.

    Peptide
    LL-37
    Outcome
    No significant changeSalivary LL-37 as caries predictor
    Study

    n = 35

    Outcome group
    Infection and antimicrobial activity · Infection

    Source sentences

    Summary
    The tested salivary parameters did not show caries-predictive significance.
    1 context sentence
    Summary · context
    For certain children (N=35), unstimulated saliva samples were collected to determine salivary pH using a digital portable pH meter and salivary levels of HNP-1, hBD-2, and LL-37 peptides using ELISA.

    This result measures the body's own LL-37. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    11 Oct 2026, 00:50 UTC

    Study results updated

  2. Version 2

    9 Oct 2026, 03:03 UTC

    Study data updated · source update from Europe PMC

  3. Version 1

    9 Oct 2026, 02:56 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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