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Study · Measured the body's own peptide · 2026

3 results

Oxytocin and rejection sensitivity: A comparative biomarker study in women with borderline personality and eating disorders.

Ruiz-Guerrero F, Gomez Del Barrio A, de la Torre-Luque A, MacDowell K, Beato-Fernández L, Castro Fuentes L, Ayad-Ahmed W, Mola P, Carrasco-Díaz Á, Lopez-Villatoro JM, Leza JC, Carrasco JL, Diaz-Marsa M

Spanish journal of psychiatry and mental health23 May 2025Cited by 1 (Europe PMC)

PMID40414356 (opens in a new tab)DOI10.1016/j.sjpmh.2025.04.002 (opens in a new tab)PepBankPUB-40414356
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

No result from this study comes from a test of the peptide.

Natural levels measured3

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01HumanEndogenous levelObservational studyOther

    In women with borderline personality disorder, plasma oxytocin was significantly lower than in women with eating disorders and healthy controls.

    In plain wordsWomen with borderline personality disorder had lower levels of the body's own oxytocin than women with eating disorders or healthy women.

    Peptide
    Oxytocin
    Outcome
    DecreasePlasma oxytocin level in BPD
    Study

    n = 108

    Comparator
    ED patients and healthy controls
    Outcome group
    Endogenous peptide levels · Mental health and mood

    Source sentences

    Summary
    BPD patients exhibited significantly lower plasma oxytocin levels vs ED patients and healthy controls.
    1 context sentence
    Summary · context
    We conducted a study including a total 108 women categorized into 3 groups: 50 with eating disorders (ED), 35 with borderline personality disorder (BPD), and 23 healthy controls.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  2. 02HumanEndogenous levelObservational studyOther

    Oxytocin receptor expression did not differ significantly across the BPD, ED and healthy control groups.

    In plain wordsOxytocin receptor expression was similar in women with borderline personality disorder, women with eating disorders and healthy women.

    Peptide
    Oxytocin
    Outcome
    No significant changeOxytocin receptor expression
    Study

    n = 108

    Comparator
    Across BPD, ED and healthy control groups
    Outcome group
    Receptor activity and mechanism · Mental health and mood

    Source sentences

    Summary
    However, oxytocin receptor expression did not differ significantly across the groups.
    1 context sentence
    Summary · context
    We conducted a study including a total 108 women categorized into 3 groups: 50 with eating disorders (ED), 35 with borderline personality disorder (BPD), and 23 healthy controls.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  3. 03HumanEndogenous levelObservational studyMechanism

    Plasma oxytocin levels were positively associated with rejection sensitivity, particularly in women with borderline personality disorder.

    In plain wordsHigher levels of the body's own oxytocin were linked to more rejection sensitivity, mainly in women with borderline personality disorder.

    Peptide
    Oxytocin
    Outcome
    IncreaseAssociation of oxytocin level with rejection sensitivity
    Study

    n = 108

    Outcome group
    Endogenous peptide levels · Mental health and mood

    Source sentences

    Summary
    Oxytocin levels were positively associated with rejection sensitivity, particularly in BPD patients.
    1 context sentence
    Summary · context
    We conducted a study including a total 108 women categorized into 3 groups: 50 with eating disorders (ED), 35 with borderline personality disorder (BPD), and 23 healthy controls.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 00:50 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:47 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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