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Study · Not a test of the peptide alone · 2025

1 result

Characterizing pleiotropy among bipolar disorder, schizophrenia, and major depression: a genome-wide cross-disorder meta-analysis.

Friligkou E, Pathak GA, Tylee DS, De Lillo A, Koller D, Cabrera-Mendoza B, Polimanti R

Psychological medicine13 May 2025Cited by 4 (Europe PMC)

PMID40357923 (opens in a new tab)PMCIDPMC12094657 (opens in a new tab)DOI10.1017/s0033291725001217 (opens in a new tab)PepBankPUB-40357923
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: CC BY-NC-ND. Results still quote short attributed sentences.

Results from this study1

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone1

In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Oxytocin.

  1. 01HumanNot a test of Oxytocin aloneObservational studyMechanism

    In a genome-wide cross-disorder analysis of schizophrenia, bipolar disorder and major depression, pleiotropic variants were enriched for the oxytocin receptor-mediated signaling pathway.

    In plain wordsIn a genetic study of three mental disorders, shared gene variants were linked to the oxytocin receptor signaling pathway.

    Peptide
    Oxytocin
    Outcome
    Not applicableEnrichment of pleiotropic variants for oxytocin receptor-mediated signaling pathway
    Study

    n: not reported in source

    Outcome group
    Receptor activity and mechanism · Mental health and mood

    Source sentences

    Summary
    oxytocin receptor-mediated signaling (p = 1.47 × 10-3)
    1 context sentence
    Summary · context
    We analyzed SCZ, BP, and MDD genome-wide association datasets available from the Psychiatric Genomics Consortium using the PLEIO framework and characterized the pleiotropic loci identified using pathway and tissue enrichment analyses.

    In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 00:50 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:48 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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