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Study · Randomized controlled trial · n = 124 · 2025

3 results

Oxytocin's role in the interaction between emotion and cognitive control.

Rosenfeld-Ganzel A, Shalev H, Hochman S, Zultan R, Cohen N, Naparstek S

Biological psychology21 Feb 2025Cited by 1 (Europe PMC)

PMID39987954 (opens in a new tab)DOI10.1016/j.biopsycho.2025.109004 (opens in a new tab)PepBankPUB-39987954
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. 3 results from people.

  1. 01HumanRandomized controlled trialEfficacy outcome

    In 124 healthy male students, intranasal oxytocin significantly reduced the effect of cognitive control on emotion versus placebo.

    In plain wordsIn healthy young men, oxytocin nose spray weakened the way mental control calms emotional reactions, compared with placebo.

    Peptide
    Oxytocin
    Outcome
    DecreaseEffect of cognitive control on emotion (emotional flanker task)
    Study

    n = 124

    Comparator
    Placebo
    Outcome group
    Anxiety and mood · Nervous system and cognition
    Studied dose
    Dose not stated · intranasalAs given in this study (human).

    Source sentences

    Summary
    Consistent with our hypotheses, we found that oxytocin significantly reduced the effect of cognitive control on emotion.
    1 context sentence
    Summary · context
    In a double-blind placebo-controlled design, 124 male students (mean age 25.18 ± 3) were administered intranasal oxytocin or a placebo and completed self-report questionnaires, an emotional flanker task, and an emotional rating task.
  2. 02HumanRandomized controlled trialEfficacy outcome

    In 124 healthy male students, intranasal oxytocin did not affect emotional experience versus placebo.

    In plain wordsIn healthy young men, oxytocin nose spray did not change how emotions were experienced, compared with placebo.

    Peptide
    Oxytocin
    Outcome
    No significant changeEmotional experience
    Study

    n = 124

    Comparator
    Placebo
    Outcome group
    Anxiety and mood · Nervous system and cognition
    Studied dose
    Dose not stated · intranasalAs given in this study (human).

    Source sentences

    Summary
    However, counter to our prediction, it did not affect emotional experience or perception.
    1 context sentence
    Summary · context
    In a double-blind placebo-controlled design, 124 male students (mean age 25.18 ± 3) were administered intranasal oxytocin or a placebo and completed self-report questionnaires, an emotional flanker task, and an emotional rating task.
  3. 03HumanRandomized controlled trialEfficacy outcome

    In 124 healthy male students, intranasal oxytocin did not affect emotional perception versus placebo.

    In plain wordsIn healthy young men, oxytocin nose spray did not change how emotions were perceived, compared with placebo.

    Peptide
    Oxytocin
    Outcome
    No significant changeEmotional perception
    Study

    n = 124

    Comparator
    Placebo
    Outcome group
    Anxiety and mood · Nervous system and cognition
    Studied dose
    Dose not stated · intranasalAs given in this study (human).

    Source sentences

    Summary
    However, counter to our prediction, it did not affect emotional experience or perception.
    1 context sentence
    Summary · context
    In a double-blind placebo-controlled design, 124 male students (mean age 25.18 ± 3) were administered intranasal oxytocin or a placebo and completed self-report questionnaires, an emotional flanker task, and an emotional rating task.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 00:50 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:47 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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