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Study · Not a test of the peptide alone · 2025

2 results

Subcutaneous route is a reliable alternative for ACTH-stimulated steroid profiling.

Dhananjaya MS, Revanasiddappa S, Kansal N, Lila AR, Sarathi V

Endocrine25 Jan 2025Cited by 1 (Europe PMC)

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone2

In this study, Cosyntropin was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Cosyntropin.

  1. 01HumanNot a test of Cosyntropin aloneRandomized controlled trialActivity measurement

    In healthy adult females, steroid levels after subcutaneous tetracosactide stimulation were comparable to those after intramuscular tetracosactide.

    In plain wordsIn healthy adult women, steroid levels after subcutaneous tetracosactide were comparable to those after intramuscular tetracosactide.

    Outcome
    Direction not reportedStimulated steroid levels by route
    Study

    n: not reported in source

    Comparator
    Intramuscular tetracosactide 250 µg
    Outcome group
    Diagnostic testing · Endocrine and hormones

    Source sentences

    Summary
    Baseline steroid levels, stimulated steroid levels, and the percentage increase in all the steroids after subcutaneous tetracosactide and acton prolongatum stimulation were comparable to those after intramuscular tetracosactide and acton prolongatum stimulation, respectively.
    2 context sentences
    Summary · context
    The study included 60 apparently-healthy adult females aged 18-40 years who were randomised to intramuscular tetracosactide (250 µg), intramuscular acton prolongatum (24 IU), subcutaneous tetracosactide (250 µg), and subcutaneous acton prolongatum (24 IU) groups in (1:1:1:1) ratio.
    Summary · context
    Serum steroid profile consisting of 13 steroids was measured at baseline and 60 minutes after ACTH stimulation by liquid chromatography-tandem mass spectrometry.

    In this study, Cosyntropin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Cosyntropin.

  2. 02HumanNot a test of Cosyntropin aloneRandomized controlled trialActivity measurement

    In healthy adult females, percentage steroid increases after subcutaneous tetracosactide were comparable to those after intramuscular tetracosactide.

    In plain wordsIn healthy adult women, percentage steroid increases after subcutaneous tetracosactide were comparable to those after intramuscular tetracosactide.

    Outcome
    Direction not reportedPercentage steroid increase by route
    Study

    n: not reported in source

    Comparator
    Intramuscular tetracosactide 250 µg
    Outcome group
    Diagnostic testing · Endocrine and hormones

    Source sentences

    Summary
    Baseline steroid levels, stimulated steroid levels, and the percentage increase in all the steroids after subcutaneous tetracosactide and acton prolongatum stimulation were comparable to those after intramuscular tetracosactide and acton prolongatum stimulation, respectively.
    2 context sentences
    Summary · context
    The study included 60 apparently-healthy adult females aged 18-40 years who were randomised to intramuscular tetracosactide (250 µg), intramuscular acton prolongatum (24 IU), subcutaneous tetracosactide (250 µg), and subcutaneous acton prolongatum (24 IU) groups in (1:1:1:1) ratio.
    Summary · context
    Serum steroid profile consisting of 13 steroids was measured at baseline and 60 minutes after ACTH stimulation by liquid chromatography-tandem mass spectrometry.

    In this study, Cosyntropin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Cosyntropin.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    28 Oct 2026, 02:03 UTC

    Study results updated

  2. Version 1

    27 Oct 2026, 16:37 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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