Skip to content

Study · Animal study (in vivo) · rat · 2025

5 results

Cerebrolysin treatment improved short-term memory deficits while simultaneously increasing hippocampal spine density in hypertensive female rats.

Espinoza I, Gómez-Villalobos MJ, Aguilar-Hernández L, Flores G, Morales-Medina JC

Behavioural brain research16 Jan 2025Cited by 3 (Europe PMC)

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: CC BY-NC. Results still quote short attributed sentences.

Results from this study5

5 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In hypertensive female rats, Cerebrolysin improved recognition memory.

    In plain wordsIn rats with hypertension, Cerebrolysin improved recognition memory.

    Outcome
    IncreaseRecognition memory
    Study

    ratn: not reported in source

    hypertensive and normotensive female rats
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Importantly, CBL treatment improved recognition memory in SHR strain.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In normotensive and hypertensive rats, Cerebrolysin increased CA1 dendritic arborization.

    In plain wordsIn rats with and without hypertension, Cerebrolysin increased CA1 dendritic branching.

    Outcome
    IncreaseCA1 dendritic arborization
    Study

    ratn: not reported in source

    hypertensive and normotensive female rats
    Outcome group
    Neuroprotection · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Moreover, CBL treatment increased arborization in both normotensive and hypertensive rats in the CA1, and DG regions of hippocampus and EC and selectively increased spine density in the hippocampus of hypertensive rats.
  3. 03AnimalAnimal study (in vivo)Efficacy outcome

    In normotensive and hypertensive rats, Cerebrolysin increased dentate gyrus dendritic arborization.

    In plain wordsIn rats with and without hypertension, Cerebrolysin increased dentate gyrus dendritic branching.

    Outcome
    IncreaseDentate gyrus dendritic arborization
    Study

    ratn: not reported in source

    hypertensive and normotensive female rats
    Outcome group
    Neuroprotection · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Moreover, CBL treatment increased arborization in both normotensive and hypertensive rats in the CA1, and DG regions of hippocampus and EC and selectively increased spine density in the hippocampus of hypertensive rats.
  4. 04AnimalAnimal study (in vivo)Efficacy outcome

    In normotensive and hypertensive rats, Cerebrolysin increased entorhinal cortex dendritic arborization.

    In plain wordsIn rats with and without hypertension, Cerebrolysin increased entorhinal cortex dendritic branching.

    Outcome
    IncreaseEntorhinal cortex dendritic arborization
    Study

    ratn: not reported in source

    hypertensive and normotensive female rats
    Outcome group
    Neuroprotection · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Moreover, CBL treatment increased arborization in both normotensive and hypertensive rats in the CA1, and DG regions of hippocampus and EC and selectively increased spine density in the hippocampus of hypertensive rats.
  5. 05AnimalAnimal study (in vivo)Efficacy outcome

    In hypertensive rats, Cerebrolysin selectively increased hippocampal spine density.

    In plain wordsIn rats with hypertension, Cerebrolysin increased hippocampal spine density.

    Outcome
    IncreaseHippocampal spine density
    Study

    ratn: not reported in source

    hypertensive and normotensive female rats
    Outcome group
    Neuroprotection · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Moreover, CBL treatment increased arborization in both normotensive and hypertensive rats in the CA1, and DG regions of hippocampus and EC and selectively increased spine density in the hippocampus of hypertensive rats.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    14 Oct 2026, 05:02 UTC

    Study results updated

  2. Version 1

    14 Oct 2026, 01:46 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

PepBank is a research reference. Talk to a doctor before you use any peptide.