In elderly patients with aMCI, annual Cerebrolysin courses reduced cognitive deficit progression compared with no therapy.
In plain wordsIn elderly patients with mild cognitive impairment, annual Cerebrolysin courses reduced cognitive decline compared with no therapy.
- Peptide
- Cerebrolysin
- Outcome
- DecreaseCognitive deficit progression
- Study
n = 100
- Comparator
- No therapy
- Outcome group
- Cognition and memory · Nervous system and cognition
- Studied dose
- 20 ml in 100 ml of saline solution, 20 infusions per annual course · intravenous · 3 years, annual 4-week coursesAs given in this study (human).
Source sentences
A comparative three-year prospective study conducted in a group of aMCI patients treated with annual course therapy with Cerebrolysin and those who did not receive therapy showed a lower progression of cognitive deficits and a significantly lower conversion rate to dementia in patients who received…
2 context sentences(design, population, supporting numbers)
In total, 100 patients with aMCI were included in the study, randomly assigned to 2 groups: patients of group 1 (n=50) received annual course therapy with Cerebrolysin for 3 years (20 intravenous infusions of Cerebrolysin 20 ml in 100 ml of saline solution for 4 weeks).
Group 2 patients underwent annual clinical examination, but did not receive therapy.