In children aged 1.5-3.5 years given weekly vitamin D3 or placebo for 6 months, the change in LL‑37/cathelicidin levels did not differ between groups.
In plain wordsIn young children, weekly vitamin D did not change the body's own LL‑37 levels compared with placebo.
- Peptide
- LL-37
- Outcome
- No significant changeChange in LL-37/cathelicidin levels after weekly vitamin D3
- Study
n: not reported in source
- Comparator
- Placebo
- Analysis
- Secondary
- Outcome group
- Immune response · Immune and inflammation
Source sentences
no group differences were observed in number of ARI (P = .85), ARI hospitalizations (P = .20), LL-37/cathelicidin change (P = .30), or adverse events (P = .41)
2 context sentences(design, population, supporting numbers)
Randomized, double-blind, placebo-controlled trial in 303 children aged 1.5-3.5 years
secondary outcomes included number of ARI hospitalizations, change of serum 25-hydroxyvitamin D (25(OH)D) and LL-37/cathelicidin levels
This result measures the body's own LL-37. Nobody was given the peptide. It is not evidence about taking it.