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Study · Measured the body's own peptide · 2024

2 results

Acute salivary antimicrobial peptide secretion response to different exercise intensities and durations.

Ito R, Uchino T, Uchida M, Fujie S, Iemitsu K, Kojima C, Nakamura M, Shimizu K, Tanimura Y, Shinohara Y, Hashimoto T, Isaka T, Iemitsu M

American journal of physiology. Regulatory, integrative and comparative physiology19 Aug 2024Cited by 2 (Europe PMC)

PMID39155711 (opens in a new tab)DOI10.1152/ajpregu.00132.2024 (opens in a new tab)PepBankPUB-39155711
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Natural levels measured2

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01HumanEndogenous levelRandomized controlled trialOther

    In 14 healthy young untrained men, salivary LL‑37 levels did not change after 30 min of cycling at 35%, 55% or 75% of maximal oxygen uptake.

    In plain wordsIn healthy young men, cycling at different intensities did not change the body's own LL‑37 levels in saliva.

    Peptide
    LL-37
    Outcome
    No significant changeSalivary LL-37 level after 30 min of cycling at 35%, 55% and 75% of maximal oxygen uptake
    Study

    n = 14

    Comparator
    Baseline (before exercise)
    Outcome group
    Immune response · Immune and inflammation

    Source sentences

    Summary
    salivary LL-37 levels did not change after exercise at any intensity
    1 context sentence
    Summary · context
    In a randomized crossover trial, 14 young healthy untrained men performed intensity trials [cycling at 35%, 55%, and 75% of maximal oxygen uptake (V̇o2max) for 30 min]

    This result measures the body's own LL-37. Nobody was given the peptide. It is not evidence about taking it.

  2. 02HumanEndogenous levelRandomized controlled trialOther

    In 14 healthy young untrained men cycling at 55% of maximal oxygen uptake, the change in salivary LL‑37 from baseline to 0 min after exercise was greater after 60 and 90 min than after 30 min.

    In plain wordsIn healthy young men, longer cycling (60 and 90 minutes) changed the body's own salivary LL‑37 more than 30 minutes did.

    Peptide
    LL-37
    Outcome
    IncreaseChange in salivary LL-37 level after 30, 60 and 90 min of cycling at 55% of maximal oxygen uptake
    Study

    n = 14

    Comparator
    30 min of cycling at 55% of maximal oxygen uptake
    Outcome group
    Immune response · Immune and inflammation

    Source sentences

    Summary
    the change in salivary levels of LL-37 and HBD-2 from baseline to 0 min after exercise at 55% V̇o2max was greater after 60 and 90 min of exercise compared with that after 30 min of exercise
    1 context sentence
    Summary · context
    duration trials (cycling at 55% V̇o2max for 30, 60, and 90 min)

    This result measures the body's own LL-37. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    9 Oct 2026, 12:39 UTC

    Study results updated

  2. Version 2

    9 Oct 2026, 03:03 UTC

    Study data updated · source update from Europe PMC

  3. Version 1

    9 Oct 2026, 02:56 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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