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Study · Observational study · n = 12 · 2024

4 results

Robust growth hormone responses to GH-releasing peptide 2 in adolescents.

Onuki T, Hiroaki T, Sawano K, Shibata N, Nyuzuki H, Ogawa Y, Okada M, Sone H, Nagasaki K

Journal of pediatric endocrinology & metabolism : JPEM4 Jul 2024

PMID38958228 (opens in a new tab)DOI10.1515/jpem-2024-0115 (opens in a new tab)PepBankPUB-38958228
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

4 results from studies that gave the peptide. 4 results from people.

  1. 01HumanObservational studyOther

    In adolescents with organic or genetic GH deficiency, the median peak GH level in the GHRP2 test was 3.4 ng/mL.

    In plain wordsIn adolescents with organic or genetic GH deficiency, growth hormone peaked at a median of 3.4 ng/mL after GHRP2.

    Peptide
    GHRP-2
    Outcome
    Not applicableMedian peak GH in GHRP2 test, organic or genetic GHD group
    Study

    n = 12

    Outcome group
    Growth hormone and IGF-1 · Endocrine and hormones
    Studied dose
    Dose not stated

    Measurements

    Median peak GH
    3.4 ng/mL
    o/gGHD group

    Source sentences

    Summary
    The median GH peak levels were 3.4 ng/mL in o/gGHD group, 88.9 ng/mL in iGHD group, and 90.1 ng/mL in SS group, indicating a robust response of GH peak levels in iGHD and SS groups.
    1 context sentence
    Summary · context
    Clinical data of adolescents after onset of puberty who underwent GHRP2T at our institution from May 2010 to March 2023 were collected retrospectively.
  2. 02HumanObservational studyOther

    In adolescents with short stature, the median peak GH level in the GHRP2 test was 90.1 ng/mL, a robust response.

    In plain wordsIn adolescents with short stature, growth hormone peaked at a median of 90.1 ng/mL after GHRP2.

    Peptide
    GHRP-2
    Outcome
    Not applicableMedian peak GH in GHRP2 test, short stature group
    Study

    n = 8

    Outcome group
    Growth hormone and IGF-1 · Endocrine and hormones
    Studied dose
    Dose not stated

    Measurements

    Median peak GH
    90.1 ng/mL
    SS group

    Source sentences

    Summary
    The median GH peak levels were 3.4 ng/mL in o/gGHD group, 88.9 ng/mL in iGHD group, and 90.1 ng/mL in SS group, indicating a robust response of GH peak levels in iGHD and SS groups.
    1 context sentence
    Summary · context
    Clinical data of adolescents after onset of puberty who underwent GHRP2T at our institution from May 2010 to March 2023 were collected retrospectively.
  3. 03HumanObservational studyOther

    In adolescents with idiopathic GH deficiency, the median peak GH level in the GHRP2 test was 88.9 ng/mL, a robust response.

    In plain wordsIn adolescents with idiopathic GH deficiency, growth hormone peaked at a median of 88.9 ng/mL after GHRP2.

    Peptide
    GHRP-2
    Outcome
    Not applicableMedian peak GH in GHRP2 test, idiopathic GHD group
    Study

    n = 3

    Outcome group
    Growth hormone and IGF-1 · Endocrine and hormones
    Studied dose
    Dose not stated

    Measurements

    Median peak GH
    88.9 ng/mL
    iGHD group

    Source sentences

    Summary
    The median GH peak levels were 3.4 ng/mL in o/gGHD group, 88.9 ng/mL in iGHD group, and 90.1 ng/mL in SS group, indicating a robust response of GH peak levels in iGHD and SS groups.
    1 context sentence
    Summary · context
    Clinical data of adolescents after onset of puberty who underwent GHRP2T at our institution from May 2010 to March 2023 were collected retrospectively.
  4. 04HumanObservational studyOther

    In adolescents, two patients exceeded the GHRP2 test cut-off but were below the cut-off in other GH tests, so the current GHRP2 cut-off may miss some GH deficiency.

    In plain wordsIn adolescents, two patients passed the GHRP2 test but failed other growth hormone tests, so the GHRP2 cut-off may miss some deficiency.

    Peptide
    GHRP-2
    Outcome
    Not applicablePatients above the GHRP2T cut-off but below the cut-off of other GH tests
    Study

    n: not reported in source

    Outcome group
    Growth hormone and IGF-1 · Endocrine and hormones
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Two patients exceeded the cut-off for GHRP2T but below for other GHT, indicating the current cut-off for GHRP2T may miss some GHD patients.
    1 context sentence
    Summary · context
    Clinical data of adolescents after onset of puberty who underwent GHRP2T at our institution from May 2010 to March 2023 were collected retrospectively.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 21:44 UTC

    Study results updated

  2. Version 1

    13 Oct 2026, 16:31 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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