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Study · Randomized controlled trial · n = 72 · 2024

4 results

Intranasal Oxytocin Improves Interoceptive Accuracy and Heartbeat-Evoked Potentials During a Cardiac Interoceptive Task.

Zhou M, Cheng L, Zhou Y, Zhu S, Zhang Y, Kendrick KM, Yao S

Biological psychiatry. Cognitive neuroscience and neuroimaging3 Jun 2024Cited by 6 (Europe PMC)

PMID38839034 (opens in a new tab)DOI10.1016/j.bpsc.2024.05.004 (opens in a new tab)PepBankPUB-38839034
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

4 results from studies that gave the peptide. 4 results from people.

  1. 01HumanRandomized controlled trialEfficacy outcome

    In healthy men, intranasal oxytocin increased interoceptive accuracy on a cardiac interoceptive task versus placebo.

    In plain wordsIn healthy men, oxytocin spray improved sensing of their own heartbeat during a task, compared with placebo.

    Peptide
    Oxytocin
    Outcome
    IncreaseInteroceptive accuracy in cardiac interoceptive task
    Study

    n = 72

    Comparator
    Placebo
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    Dose not stated · intranasalAs given in this study (human).

    Source sentences

    Summary
    in the interoceptive task, oxytocin increased interoceptive accuracy at the behavioral level
    1 context sentence
    Summary · context
    Using a double-blind, placebo-controlled, between-participant design, we recruited 72 healthy male participants who performed a cardiac interoceptive task during electroencephalograph and electrocardiograph recording to examine whether intranasal administration of the neuropeptide oxytocin could mod…
  2. 02HumanRandomized controlled trialMechanism

    In healthy men, intranasal oxytocin increased heartbeat-evoked potential amplitudes in frontocentral and central regions during the interoceptive task.

    In plain wordsIn healthy men, oxytocin spray raised brain responses to heartbeats during a task, compared with placebo.

    Peptide
    Oxytocin
    Outcome
    IncreaseHeartbeat-evoked potential amplitude
    Study

    n = 72

    Comparator
    Placebo
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    Dose not stated · intranasalAs given in this study (human).

    Source sentences

    Summary
    paralleled by larger heartbeat-evoked potential amplitudes in frontocentral and central regions on the neural level
    1 context sentence
    Summary · context
    Using a double-blind, placebo-controlled, between-participant design, we recruited 72 healthy male participants who performed a cardiac interoceptive task during electroencephalograph and electrocardiograph recording to examine whether intranasal administration of the neuropeptide oxytocin could mod…
  3. 03HumanRandomized controlled trialMechanism

    In healthy men, intranasal oxytocin had no significant effect on electroencephalograph during resting state.

    In plain wordsIn healthy men, oxytocin spray did not change resting brain activity compared with placebo.

    Peptide
    Oxytocin
    Outcome
    No significant changeResting-state electroencephalograph
    Study

    n = 72

    Comparator
    Placebo
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    Dose not stated · intranasalAs given in this study (human).

    Source sentences

    Summary
    However, there were no significant effects of oxytocin on electroencephalograph or electrocardiograph during resting state.
    1 context sentence
    Summary · context
    Using a double-blind, placebo-controlled, between-participant design, we recruited 72 healthy male participants who performed a cardiac interoceptive task during electroencephalograph and electrocardiograph recording to examine whether intranasal administration of the neuropeptide oxytocin could mod…
  4. 04HumanRandomized controlled trialMechanism

    In healthy men, intranasal oxytocin had no significant effect on electrocardiograph during resting state.

    In plain wordsIn healthy men, oxytocin spray did not change resting heart recordings compared with placebo.

    Peptide
    Oxytocin
    Outcome
    No significant changeResting-state electrocardiograph
    Study

    n = 72

    Comparator
    Placebo
    Outcome group
    Heart function · Cardiovascular
    Studied dose
    Dose not stated · intranasalAs given in this study (human).

    Source sentences

    Summary
    However, there were no significant effects of oxytocin on electroencephalograph or electrocardiograph during resting state.
    1 context sentence
    Summary · context
    Using a double-blind, placebo-controlled, between-participant design, we recruited 72 healthy male participants who performed a cardiac interoceptive task during electroencephalograph and electrocardiograph recording to examine whether intranasal administration of the neuropeptide oxytocin could mod…

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 00:50 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:47 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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