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Study · Animal study (in vivo) · mouse · 2024

2 results

Lactobacillus reuteri JCM 1112 ameliorates chronic acrylamide-induced glucose metabolism disorder via the bile acid-TGR5-GLP-1 axis and modulates intestinal oxidative stress in mice.

Yue Z, Zhao F, Guo Y, Zhang Y, Chen Y, He L, Li L

Food & function17 Jun 2024Cited by 16 (Europe PMC)

PMID38804210 (opens in a new tab)DOI10.1039/d4fo01061b (opens in a new tab)PepBankPUB-38804210
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In acrylamide-exposed mice, dulaglutide decreased blood glucose compared with untreated exposure.

    In plain wordsIn mice exposed to acrylamide, dulaglutide lowered blood sugar compared with untreated exposure.

    Peptide
    Dulaglutide (Trulicity)
    Outcome
    DecreaseBlood glucose
    Study

    mousen: not reported in source

    C57BL/6N mice exposed to chronic low-dose acrylamide
    Comparator
    Acrylamide exposure without dulaglutide
    Outcome group
    Glycemic control · Metabolic and weight
    Studied dose
    Dose not stated · 3 weeksAs given in this study (mouse).

    Source sentences

    Summary
    whereas dulaglutide treatment decreased the blood glucose level and increased the serum insulin level in AA-exposed mice.
    1 context sentence
    Summary · context
    Here, C57BL/6N mice were orally administered with 5 mg per kg bw AA for 10 weeks, followed by another 3 weeks of glucagon-like peptide-1 (GLP-1) analogue (dulaglutide) treatment.
  2. 02AnimalAnimal study (in vivo)Mechanism

    In acrylamide-exposed mice, dulaglutide increased serum insulin compared with untreated exposure.

    In plain wordsIn mice exposed to acrylamide, dulaglutide increased blood insulin compared with untreated exposure.

    Peptide
    Dulaglutide (Trulicity)
    Outcome
    IncreaseSerum insulin
    Study

    mousen: not reported in source

    C57BL/6N mice exposed to chronic low-dose acrylamide
    Comparator
    Acrylamide exposure without dulaglutide
    Outcome group
    Glycemic control · Endocrine and hormones
    Studied dose
    Dose not stated · 3 weeksAs given in this study (mouse).

    Source sentences

    Summary
    whereas dulaglutide treatment decreased the blood glucose level and increased the serum insulin level in AA-exposed mice.
    1 context sentence
    Summary · context
    Here, C57BL/6N mice were orally administered with 5 mg per kg bw AA for 10 weeks, followed by another 3 weeks of glucagon-like peptide-1 (GLP-1) analogue (dulaglutide) treatment.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    22 Oct 2026, 02:25 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 18:59 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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