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Study · Measured the body's own peptide · 2024

3 results

An 8-Week study on the effects of high and Moderate-Intensity interval exercises on mitochondrial MOTS-C changes and their relation to metabolic markers in male diabetic sand rats.

Parseh S, Shakerian S, Reza Tabandeh M, Habibi A

Diabetes research and clinical practice16 Apr 2024Cited by 2 (Europe PMC)

PMID38636847 (opens in a new tab)DOI10.1016/j.diabres.2024.111656 (opens in a new tab)PepBankPUB-38636847
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

No result from this study comes from a test of the peptide.

Natural levels measured3

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01AnimalEndogenous levelAnimal study (in vivo)Other

    In male sand rats, both exercise intensity and diabetes significantly affected the body's own MOTS‑C protein levels.

    In plain wordsIn sand rats, exercise intensity and diabetes both changed the body's own MOTS‑C levels.

    Peptide
    MOTS-c
    Outcome
    Direction not reportedMOTS-C protein level by exercise intensity and diabetes
    Study

    sand ratn = 30

    Male sand rats with high-fat diet plus streptozotocin diabetes, 8 weeks of interval exercise
    Outcome group
    Mitochondrial function · Metabolic and weight

    Source sentences

    Summary
    Both exercise intensity and diabetes significantly affected the levels of PCG-1a, MOTS-C, GLUT4 proteins, and insulin resistance (p < 0.001).
    2 context sentences
    Summary · context
    Thirty male sand rats were divided into six groups: control, MIIT, DM + HIIT, DM + MIIT, DM, and HIIT (5 rats each).
    Summary · context
    The Wistar sand rats in exercise groups underwent 8 weeks of interval training of varying intensities.

    This result measures the body's own MOTS-c. Nobody was given the peptide. It is not evidence about taking it.

  2. 02AnimalEndogenous levelAnimal study (in vivo)Other

    In male sand rats, the combined effect of diabetes status and exercise intensity on the body's own MOTS‑C protein level was significant.

    In plain wordsIn sand rats, diabetes and exercise intensity together changed the body's own MOTS‑C levels.

    Peptide
    MOTS-c
    Outcome
    Direction not reportedMOTS-C protein level, diabetes by exercise intensity interaction
    Study

    sand ratn = 30

    Male sand rats with high-fat diet plus streptozotocin diabetes, 8 weeks of interval exercise
    Outcome group
    Mitochondrial function · Metabolic and weight

    Source sentences

    Summary
    The combined effect of diabetes status and exercise intensity on these levels was also significant (p < 0.001).
    2 context sentences
    Summary · context
    Thirty male sand rats were divided into six groups: control, MIIT, DM + HIIT, DM + MIIT, DM, and HIIT (5 rats each).
    Summary · context
    The Wistar sand rats in exercise groups underwent 8 weeks of interval training of varying intensities.

    This result measures the body's own MOTS-c. Nobody was given the peptide. It is not evidence about taking it.

  3. 03AnimalEndogenous levelAnimal study (in vivo)Other

    In diabetic male sand rats, the moderate-intensity exercise group showed higher levels of the body's own MOTS‑C protein.

    In plain wordsIn diabetic sand rats, moderate exercise went with higher levels of the body's own MOTS‑C.

    Peptide
    MOTS-c
    Outcome
    IncreaseMOTS-C protein level in diabetic rats with moderate-intensity exercise
    Study

    sand ratn: not reported in source

    Male sand rats with high-fat diet plus streptozotocin diabetes, 8 weeks of interval exercise
    Outcome group
    Mitochondrial function · Metabolic and weight

    Source sentences

    Summary
    The moderate-intensity exercise group with diabetes showed higher levels of PCG-1a, MOTS-C, and GLUT4 proteins and reduced insulin resistance levels (p < 0.001).
    2 context sentences
    Summary · context
    Thirty male sand rats were divided into six groups: control, MIIT, DM + HIIT, DM + MIIT, DM, and HIIT (5 rats each).
    Summary · context
    The Wistar sand rats in exercise groups underwent 8 weeks of interval training of varying intensities.

    This result measures the body's own MOTS-c. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    9 Oct 2026, 18:17 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:47 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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