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Study · Randomized controlled trial · 2024

2 results

The Effects of Combined Use of Linaclotide and Polyethylene Glycol Electrolyte Powder in Colonoscopy Preparation for Patients With Chronic Constipation.

Song J, Xu Y, Chen C, Qi X, Hu P, Ying X, Li H

Surgical laparoscopy, endoscopy & percutaneous techniques1 Apr 2024Cited by 11 (Europe PMC)

PMID38444073 (opens in a new tab)DOI10.1097/sle.0000000000001273 (opens in a new tab)PepBankPUB-38444073
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. 2 results from people.

  1. 01HumanRandomized controlled trialEfficacy outcome

    In patients with chronic constipation, 3L PEG plus linaclotide was superior to 3L PEG on right-colon, transverse-colon, total BBPS and total OBPQS scores (P <0.05).

    In plain wordsIn patients with chronic constipation, adding linaclotide to 3L PEG gave better bowel preparation scores than 3L PEG alone.

    Peptide
    Linaclotide
    Outcome
    Direction not reportedBowel preparation scores
    Study

    n: not reported in source

    Comparator
    3L PEG
    Outcome group
    Bowel Preparation · Gastrointestinal
    Studied dose
    Dose not stated

    Source sentences

    Summary
    In terms of the score of the right half of the colon, the score of the transverse colon, the total score using BBPS, and the total score using OBPQS, the 3L PEG (polyethylene glycol)+L group was superior to groups 3L PEG and 2L PEG+L ( P 0.05).
    2 context sentences
    Summary · context
    We included 260 patients with chronic constipation who were scheduled to undergo a colonoscopy.
    Summary · context
    They were equally divided into 4 groups using a random number table: 4L PEG, 3L PEG, 3L PEG+L, and 2L PEG+L.
  2. 02HumanRandomized controlled trialEfficacy outcome

    In patients with chronic constipation, colonoscope withdrawal time was shorter with 3L PEG plus linaclotide than 3L PEG (P <0.05).

    In plain wordsAdding linaclotide to 3L PEG shortened colonoscope withdrawal time compared with 3L PEG alone.

    Peptide
    Linaclotide
    Outcome
    DecreaseColonoscope withdrawal time
    Study

    n: not reported in source

    Comparator
    3L PEG
    Outcome group
    Bowel Preparation · Gastrointestinal
    Studied dose
    Dose not stated

    Source sentences

    Summary
    The colonoscope withdrawal time in the 3L PEG+L group was shorter than in groups 4L PEG and 3L PEG ( P 0.05).
    2 context sentences
    Summary · context
    We included 260 patients with chronic constipation who were scheduled to undergo a colonoscopy.
    Summary · context
    They were equally divided into 4 groups using a random number table: 4L PEG, 3L PEG, 3L PEG+L, and 2L PEG+L.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    28 Oct 2026, 02:03 UTC

    Study results updated

  2. Version 1

    27 Oct 2026, 16:34 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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