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Study · Not a test of the peptide alone · 2023

4 results

Polydioxanone Bioactive Sutures-Acetyl Hexapeptide-8 (Argireline): An Intelligent System for Controlled Release in Facial Harmonization.

Velazco de Maldonado GJ, Suárez-Vega DV, Miller-Kobisher B, García-Guevara VJ

Journal of cutaneous and aesthetic surgery1 Oct 2023Cited by 1 (Europe PMC)

PMID38314369 (opens in a new tab)PMCIDPMC10833482 (opens in a new tab)DOI10.4103/jcas.jcas_34_23 (opens in a new tab)PepBankPUB-38314369
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: CC BY-NC. Results still quote short attributed sentences.

Results from this study4

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone4

In this study, Argireline (acetyl hexapeptide-8) was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Argireline (acetyl hexapeptide-8).

  1. 01LabNot a test of Argireline (acetyl hexapeptide-8) aloneIn vitro (cell-free)Activity measurement

    In laboratory tests, PDO threads absorbed Argireline through capillarity and doubled their weight every 24 h.

    In plain wordsIn lab tests, PDO threads absorbed Argireline and doubled their weight every 24 hours.

    Peptide
    Argireline (acetyl hexapeptide-8)
    Outcome
    IncreaseThread weight
    Study

    n: not reported in source

    PDO threads immersed in Argireline
    Outcome group
    Pharmacokinetics · Pharmacology

    Source sentences

    Summary
    The electronic weighing revealed that the PDO thread enjoys capillarity by the peptide, doubling its weight every 24 h.
    2 context sentences
    Summary · context
    Three segments of 1-cm long 21G PDO threads immersed in 1 mL of Arg.
    Summary · context
    They were also weighed before and after being soaked in Arg, and employing ultraviolet (UV)-visible spectroscopy, the release rate of Arg from the PDO suture was measured.

    In this study, Argireline (acetyl hexapeptide-8) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Argireline (acetyl hexapeptide-8).

  2. 02LabNot a test of Argireline (acetyl hexapeptide-8) aloneIn vitro (cell-free)Activity measurement

    In laboratory tests, PDO threads sustained Argireline release for 1 h.

    In plain wordsIn lab tests, PDO threads released Argireline for 1 hour.

    Peptide
    Argireline (acetyl hexapeptide-8)
    Outcome
    Not applicableSustained peptide release
    Study

    n: not reported in source

    PDO threads immersed in Argireline
    Outcome group
    Pharmacokinetics · Pharmacology

    Measurements

    Sustained release duration
    1 h
    Argireline from PDO threads

    Source sentences

    Summary
    UV spectra revealed that PDO thread is a well-controlled release system for Arg, allowing its sustained release for 1 h.
    2 context sentences
    Summary · context
    Three segments of 1-cm long 21G PDO threads immersed in 1 mL of Arg.
    Summary · context
    They were also weighed before and after being soaked in Arg, and employing ultraviolet (UV)-visible spectroscopy, the release rate of Arg from the PDO suture was measured.

    In this study, Argireline (acetyl hexapeptide-8) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Argireline (acetyl hexapeptide-8).

  3. 03LabNot a test of Argireline (acetyl hexapeptide-8) aloneIn vitro (cell-free)Activity measurement

    In laboratory microscopy, PDO threads swelled as they absorbed Argireline by capillarity.

    In plain wordsIn lab tests, PDO threads swelled as they absorbed Argireline.

    Peptide
    Argireline (acetyl hexapeptide-8)
    Outcome
    IncreaseThread swelling
    Study

    n: not reported in source

    PDO threads immersed in Argireline
    Outcome group
    Pharmacokinetics · Pharmacology

    Source sentences

    Summary
    Optical and electronic photomicrographs confirm the swelling of the PDO thread by absorbing Arg by its capillarity, but this hydrophilicity does not lead to its premature physical degradation.
    2 context sentences
    Summary · context
    Three segments of 1-cm long 21G PDO threads immersed in 1 mL of Arg.
    Summary · context
    They were also weighed before and after being soaked in Arg, and employing ultraviolet (UV)-visible spectroscopy, the release rate of Arg from the PDO suture was measured.

    In this study, Argireline (acetyl hexapeptide-8) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Argireline (acetyl hexapeptide-8).

  4. 04LabNot a test of Argireline (acetyl hexapeptide-8) aloneIn vitro (cell-free)Activity measurement

    In laboratory microscopy, Argireline-associated hydrophilicity did not cause premature physical degradation of PDO threads.

    In plain wordsIn lab tests, Argireline absorption did not cause PDO threads to degrade prematurely.

    Peptide
    Argireline (acetyl hexapeptide-8)
    Outcome
    No significant changePremature physical degradation
    Study

    n: not reported in source

    PDO threads immersed in Argireline
    Outcome group
    Pharmacokinetics · Pharmacology

    Source sentences

    Summary
    Optical and electronic photomicrographs confirm the swelling of the PDO thread by absorbing Arg by its capillarity, but this hydrophilicity does not lead to its premature physical degradation.
    2 context sentences
    Summary · context
    Three segments of 1-cm long 21G PDO threads immersed in 1 mL of Arg.
    Summary · context
    They were also weighed before and after being soaked in Arg, and employing ultraviolet (UV)-visible spectroscopy, the release rate of Arg from the PDO suture was measured.

    In this study, Argireline (acetyl hexapeptide-8) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Argireline (acetyl hexapeptide-8).

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    22 Oct 2026, 02:25 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 18:59 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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