In EGFP-NF-L reporter PC12 cells, testing with Cerebrolysin demonstrated a robust, specific, and reproducible Neurofilament-L Bioassay.
In plain wordsIn cells, testing with Cerebrolysin demonstrated a robust, specific, and reproducible Neurofilament-L Bioassay.
- Peptide
- Cerebrolysin
- Outcome
- Not applicableNeurofilament-L Bioassay performance
- Study
ratn: not reported in source
EGFP-NF-L reporter PC12 cells- Outcome group
- Receptor activity and mechanism · Pharmacology
Source sentences
Using Cerebrolysin® as a role model for a pharmacological compound that stimulates neurotrophic activity in the central nervous system, the Neurofilament-L Bioassay was proved to be a robust, specific, and reproducible method.
1 context sentence(design, population, supporting numbers)
We generated and characterized an enhanced green fluorescent protein (EGFP)-NF-L reporter PC12 cell line for the development of a cell-based assay (designated Neurofilament-L Bioassay) that allows straightforward quantification of early neuronal differentiation based on NF-L expression.
In this study, Cerebrolysin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Cerebrolysin.