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Study · Animal study (in vivo) · sheep · 2024

3 results

Sexual behaviour of young rams is improved and less stressful after intranasal administration of oxytocin.

Damián JP, Castillo L, Pons V, Gil J, Suárez G, Terrazas A, González D, van Lier E, Banchero G

Domestic animal endocrinology28 Dec 2023

PMID38217918 (opens in a new tab)DOI10.1016/j.domaniend.2023.106837 (opens in a new tab)PepBankPUB-38217918
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In young rams in sexual tests with ewes, intranasal oxytocin reduced flehmen behaviour compared with saline.

    In plain wordsIn rams, oxytocin given in the nose led to less flehmen behaviour than saline did.

    Peptide
    Oxytocin
    Outcome
    DecreaseFlehmen behaviour
    Study

    sheepn = 10

    young rams in sexual tests with oestrous ewes
    Comparator
    Isotonic saline spray
    Outcome group
    Sexual function · Reproductive and sexual health
    Studied dose
    24 IU · intranasalAs given in this study (sheep).

    Source sentences

    Summary
    Less flehmen was observed in the OTG
    2 context sentences
    Summary · context
    Ten rams were used in a cross-over design.
    Summary · context
    At Day 0, the control group (CG, n = 5) received isotonic saline spray intranasally, and the treated group (OTG, n = 5) received oxytocin (24 IU) intranasally, 40 min before the sexual test.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In young rams in sexual tests with ewes, intranasal oxytocin increased mounts with ejaculation compared with saline.

    In plain wordsIn rams, oxytocin given in the nose led to more mounts with ejaculation than saline did.

    Peptide
    Oxytocin
    Outcome
    IncreaseMounts with ejaculation
    Study

    sheepn = 10

    young rams in sexual tests with oestrous ewes
    Comparator
    Isotonic saline spray
    Outcome group
    Sexual function · Reproductive and sexual health
    Studied dose
    24 IU · intranasalAs given in this study (sheep).

    Source sentences

    Summary
    mounts with ejaculation were increased.
    2 context sentences
    Summary · context
    Ten rams were used in a cross-over design.
    Summary · context
    At Day 0, the control group (CG, n = 5) received isotonic saline spray intranasally, and the treated group (OTG, n = 5) received oxytocin (24 IU) intranasally, 40 min before the sexual test.
  3. 03AnimalAnimal study (in vivo)Efficacy outcome

    In young rams in sexual tests with ewes, intranasal oxytocin gave lower serum cortisol than saline.

    In plain wordsIn rams, oxytocin given in the nose led to lower blood cortisol than saline did.

    Peptide
    Oxytocin
    Outcome
    DecreaseSerum cortisol concentration
    Study

    sheepn = 10

    young rams in sexual tests with oestrous ewes
    Comparator
    Isotonic saline spray
    Outcome group
    Stress hormones · Endocrine and hormones
    Studied dose
    24 IU · intranasalAs given in this study (sheep).

    Source sentences

    Summary
    The OTG presented lower serum cortisol concentration than the CG.
    2 context sentences
    Summary · context
    Ten rams were used in a cross-over design.
    Summary · context
    At Day 0, the control group (CG, n = 5) received isotonic saline spray intranasally, and the treated group (OTG, n = 5) received oxytocin (24 IU) intranasally, 40 min before the sexual test.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 00:50 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:48 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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