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Study · Not a test of the peptide alone · 2023

4 results

Ultrasensitive and Label-Free Detection of Copper Ions by GHK-Modified Asymmetric Nanochannels.

An P, Zhang Z, Yang J, Wang T, Wang Z, Sun CL, Qin C, Li J

Analytical chemistry25 Aug 2023Cited by 10 (Europe PMC)

PMID37624577 (opens in a new tab)DOI10.1021/acs.analchem.3c01174 (opens in a new tab)PepBankPUB-37624577
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone4

In this study, GHK-Cu was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking GHK-Cu.

  1. 01LabNot a test of GHK-Cu aloneIn vitro (cell-free)Other

    GHK-modified asymmetric nanochannels detected Cu2+ ions at ultra-trace level, with a detection limit of 10^-15 M.

    In plain wordsIn lab tests, nanochannels coated with GHK detected extremely small amounts of copper ions.

    Peptide
    GHK-Cu
    Outcome
    Not applicableDetection of Cu2+ ions with GHK-modified nanochannels
    Study

    n: not reported in source

    Outcome group
    Analytical methods and detection · Pharmacology

    Source sentences

    Summary
    This modification facilitated specific recognition and ultra-trace level detection of Cu2+ ions, achieving a detection limit of 10-15 M.

    In this study, GHK-Cu was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHK-Cu.

  2. 02LabNot a test of GHK-Cu aloneIn vitro (cell-free)Other

    GHK‑Cu complexes in the nanochannels could be dissociated by adding EDTA, which allowed regeneration and reuse of the detection system.

    In plain wordsIn lab tests, adding EDTA released the copper from GHK, so the sensor could be reused.

    Peptide
    GHK-Cu
    Outcome
    Not applicableRegeneration of the GHK-modified nanochannel sensor
    Study

    n: not reported in source

    Outcome group
    Analytical methods and detection · Pharmacology

    Source sentences

    Summary
    The GHK-Cu complexes could be dissociated by adding EDTA to the solution, enabling the regeneration and reuse of this ultrasensitive and label-free Cu2+ detection system using GHK-modified asymmetric multi-nanochannels.

    In this study, GHK-Cu was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHK-Cu.

  3. 03LabNot a test of GHK-Cu aloneOther designOther

    High-purity GHK peptide was synthesized using a photocleavable protecting group and auxiliary carrier.

    In plain wordsIn the lab, scientists made high-purity GHK peptide using a removable protecting group.

    Peptide
    GHK-Cu
    Outcome
    Not applicableSynthesis of high-purity GHK peptide
    Study

    n: not reported in source

    Outcome group
    Analytical methods and detection · Pharmacology

    Source sentences

    Summary
    In this work, high-purity glycyl-l-histidyl-l-lysine (GHK) peptide is synthesized by using 7-diphenylphosphonooxycoumarin-4-methanol (DPCM) as a protecting group and auxiliary carrier by homogeneous synthesis of photocleavable groups.

    In this study, GHK-Cu was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHK-Cu.

  4. 04Computer modelNot a test of GHK-Cu aloneIn silicoOther

    Theoretical calculations confirmed a high affinity of the GHK peptide for Cu2+.

    In plain wordsComputer calculations showed that GHK binds copper ions strongly.

    Peptide
    GHK-Cu
    Outcome
    Not applicableAffinity of GHK peptide for Cu2+
    Study

    n: not reported in source

    Outcome group
    Analytical methods and detection · Pharmacology

    Source sentences

    Summary
    Theoretical calculations confirmed the high affinity of the GHK peptide for Cu2+, thereby ensuring excellent Cu2+ selectivity.

    In this study, GHK-Cu was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHK-Cu.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    9 Oct 2026, 18:17 UTC

    Study results updated

  2. Version 2

    9 Oct 2026, 03:03 UTC

    Study data updated · source update from Europe PMC

  3. Version 1

    9 Oct 2026, 02:56 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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