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Study · Measured the body's own peptide · 2023

2 results

Biological marker of withdrawal ruptures: Dyadic pattern of incongruence in oxytocin release.

Tal S, Tchizick A, Shamay-Tsoory S, Dolev-Amit T, Zilcha-Mano S

Journal of counseling psychology13 Jul 2023Cited by 1 (Europe PMC)

PMID37439738 (opens in a new tab)DOI10.1037/cou0000693 (opens in a new tab)PepBankPUB-37439738
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Natural levels measured2

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01HumanEndogenous levelObservational studyOther

    In patient-therapist dyads in depression treatment, oxytocin incongruence did not predict withdrawal ruptures as a main effect.

    In plain wordsIn therapy for depression, a mismatch between patient and therapist natural oxytocin changes did not by itself predict alliance ruptures.

    Peptide
    Oxytocin
    Outcome
    No significant changeWithdrawal ruptures and patient-therapist oxytocin incongruence (Hypothesis 1)
    Study

    n = 53

    Outcome group
    Social behavior and cognition · Mental health and mood

    Source sentences

    Summary
    Only Hypothesis 2 received empirical support, meaning it was only when anxious attachment orientation was low that there were significantly more withdrawal ruptures when the patient's OT increase was higher than their therapist's OT increase.
    1 context sentence
    Summary · context
    Surface analysis was conducted on 628 saliva samples that were gathered before and after therapeutic sessions of 53 patient-therapist dyads enrolled in a randomized control trial treating major depression.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  2. 02HumanEndogenous levelObservational studyOther

    In patient-therapist dyads in depression treatment, withdrawal ruptures were more frequent when the patient's natural oxytocin increase exceeded the therapist's, only when anxious attachment orientation was low.

    In plain wordsIn therapy for depression, the body's own oxytocin rose more in patients than in therapists during more alliance ruptures, linked to low anxious attachment.

    Peptide
    Oxytocin
    Outcome
    IncreaseWithdrawal ruptures when patient oxytocin increase exceeds therapist increase, by anxious attachment (Hypothesis 2)
    Study

    n = 53

    Outcome group
    Social behavior and cognition · Mental health and mood

    Source sentences

    Summary
    Only Hypothesis 2 received empirical support, meaning it was only when anxious attachment orientation was low that there were significantly more withdrawal ruptures when the patient's OT increase was higher than their therapist's OT increase.
    1 context sentence
    Summary · context
    Surface analysis was conducted on 628 saliva samples that were gathered before and after therapeutic sessions of 53 patient-therapist dyads enrolled in a randomized control trial treating major depression.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 00:50 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:48 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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